Results 101 to 110 of about 15,684,009 (290)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

High‐Performance Bio‐Glue From the Berries of a Parasitic Plant

Advanced Materials, EarlyView.
We report a fully bio‐based adhesive derived primarily from a (poly)saccharide extract obtained from the berries of the hemi‐parasitic plant mistletoe (Viscum album), supplemented with tannic and malic acid without any further chemical functionalization.
Ufuk Gürer, Jana T. Reh, Jonas Röder, Umut Günsel, Chiara Gunnella, Lisa Schöbel, Franz Hagn, Aldo R. Boccaccini, Oliver Lieleg   +8 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Propensity to sell stocks in an artificial stock market.

PLoS ONE, 2019
This experimental study of an artificial stock market investigates what explains the propensity to sell stocks and thus the disposition effect. It is a framed field experiment that follows the steps of a previous observational study of investor behavior ...
Wlademir Prates, Newton Da Costa, Manuel Rocha Armada, Sergio Da Silva   +3 more
doaj   +1 more source

An experimental analysis of the disposition effect: Who and when?

Journal of Behavioral and Experimental Economics, 2019
The disposition effect (DE) is a common bias by which investors tend to sell winning assets too soon and hold losing assets too long. We complement the existing evidence in three directions.
Carlos Cueva, Iñigo Iturbe-Ormaetxe, Giovanni Ponti, Josefa Tomás   +3 more
semanticscholar   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

Defect‐Engineered Microwave‐Responsive Ni@C Composites From Waste PET for Catalytic Plastic Upcycling

Advanced Materials, EarlyView.
A circular upcycling strategy transforms waste poly(ethylene terephthalate) bottles into microwave‐responsive Ni@C catalyst featuring lattice‐distorted nickel cores and defective carbon shells. These strain‐rich heterointerfaces enhance dielectric loss and promote localized microwave hotspots, accelerating peroxymonosulfate activation and polymer‐chain
Xiao Lu, Shiying Ren, Jingkai Lin, Kunsheng Hu, Yalan Mo, Shaobin Wang, Wenjie Tian, Xiaoguang Duan   +7 more
wiley   +1 more source

The Disposition Effect and Momentum

, 2002
Prior experimental and empirical research documents that many investors have a lower propensity to sell those stocks on which they have a capital loss. This behavioral phenomenon, known as \the disposition effect, has implications for equilibrium prices.
Mark Grinblatt, Bing Han
openaire   +1 more source

Metastable Polymers for Circular 3D Printing

Advanced Materials, EarlyView.
3D‐printed polymers are usually permanent and hard to recycle. Here, metastable polymers are designed to fall apart on demand. A chemical trigger unzips the printed material back into its original building blocks within minutes at room temperature.
Johannes Markhart, Philipp Mainik, Eva Blasco   +2 more
wiley   +1 more source

The effects of procrastination on physical activity among Chinese university students: the chain-mediated effects of time management disposition and exercise motivation

Frontiers in Psychology
ObjectivesGrounded in self-determination theory (SDT), the procrastination-health model, and the mechanism model of exercise persistence, this study examined the effects of procrastination on physical activity and the mechanism of its action in Chinese ...
Yuan Zhang, Maoshen Tian, Jian Yang, Yue Xi, Zhihui Li, Lin Wang   +5 more
doaj   +1 more source