Results 211 to 220 of about 1,230,257 (264)

The Silent Saboteur: Teaching the Clinical Implications of Occult Hypoxemia & Social Determinants of Health via a Pulmonary Embolism Case. [PDF]

J Educ Teach Emerg Med
Marrone E, Cafaro J, Klein J.
europepmc   +1 more source

Whole-Body Physiologically Based Pharmacokinetic Modeling of GalNAc-Conjugated siRNAs. [PDF]

Pharmaceutics
Salim EL, Kristensen K, Sjögren E.
europepmc   +1 more source

Surgical Management of Facet Fracture Dislocations of the Subaxial Spine: A Retrospective Cohort Study. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Callaway J, Shahzad H, Tse S, Frei A, Javidan Y, Roberto R, Le H.   +6 more
europepmc   +1 more source

PBPK Modeling: Empowering Drug Development and Precision Dosing in China. [PDF]

CPT Pharmacometrics Syst Pharmacol
Yang D, Li J, Mak WY, Zheng A, Zhu X, He Q, Wang Y, Xiang X.   +7 more
europepmc   +1 more source

Determinants of Disposition and Reverse Disposition Effects [PDF]

SSRN Electronic Journal, 2009
We develop a new measure for disposition effects based on the average length of a trading strategy and whether it is loss-making or profitable. Using this new measure, we are able to evaluate disposition effects in more detail than has been possible previously. We find for the first time the existence of disposition and reverse disposition effects. The
Andreas Krause, K.C. John Wei, Zhishu Yang   +2 more
openaire   +1 more source

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Cotinine disposition and effects

Clinical Pharmacology and Therapeutics, 1983
Cotinine is the major metabolite of nicotine in man. We studied cotinine disposition kinetics in 28 healthy habitual cigarette smokers. Eight subjects received cotinine fumarate, 4 micrograms base/kg/min IV for 60 min. Mean (+/- SD) metabolic clearance was 60 +/- 12 ml/min and mean renal clearance was 12 +/- 5 ml/min, averaging 17% of total clearance ...
Abdel‐Latif Osman, Florence Kuyt, Neal L. Benowitz, Peyton Jacob, Reese T Jones   +4 more
openaire   +2 more sources

Disposition kinetics and effects of menthol

Clinical Pharmacology & Therapeutics, 1999
Menthol is widely used in a variety of commercial products and foods, but its clinical pharmacology is not well studied. To determine the disposition kinetics and to examine subjective and cardiovascular effects of menthol, we conducted a crossover placebo-controlled study that compared pure menthol versus placebo, along with an uncontrolled exposure ...
Peyton Jacob, Peyton Jacob, Neal L. Benowitz, Neal L. Benowitz, Lisa Yu, Lisa Yu, Ayse Gelal, Ayse Gelal   +7 more
openaire   +5 more sources