Results 141 to 150 of about 6,509 (259)

The unbearable (financial) burdens of parenting

The British Journal of Sociology, EarlyView.
Alya Guseva
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Disproportionality Analysis and Timing of Drug-Associated Guillain-Barré Syndrome Onset Based on the Japanese Adverse Drug Event Report Database. [PDF]

Pharmaceuticals (Basel)
Toriumi S, Kurihara Y, Shimokawa K, Tanaka A, Araki N, Kawai O, Sugiura Y, Uesawa Y.   +7 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Spectrum and signals of medication-associated cognitive disorder: a comprehensive disproportionality analysis with cross-database validation. [PDF]

Front Pharmacol
Wen H, Dong Y, Wang R.
europepmc   +1 more source

Bruton tyrosine kinase inhibitors and cardiovascular adverse events

British Journal of Pharmacology, EarlyView.
Abstract Bruton tyrosine kinase inhibitors (BTKi) have transformed the management of chronic lymphocytic leukaemia and other B‐cell malignancies, yet their therapeutic benefit is tempered by clinically relevant cardiovascular toxicities (predominantly atrial fibrillation, hypertension, bleeding and ventricular arrhythmias).
Massimiliano Camilli, Cristina Madaudo, Emanuela Salvatorelli, Giorgio Minotti, Pierantonio Menna   +4 more
wiley   +1 more source

Cardiovascular Safety Signals of Oral Versus Topical Minoxidil in FAERS: A Disproportionality Analysis (Analytic Cohort 2012-2025). [PDF]

Life (Basel)
Makkena HB, Kasu V.
europepmc   +1 more source

The Capability Approach as the Ethics of Social Work With Child Refugees

Child &Family Social Work, EarlyView.
ABSTRACT This article examines the capability approach (CA) as an ethical framework for social work practice with minor refugees. Drawing on the foundational work of Amartya Sen and Martha Nussbaum, as well as its recent application to child welfare contexts, the article argues that conventional rights–based and deficit‐oriented approaches are ...
Gottfried Schweiger
wiley   +1 more source

Hepatotoxicity Associated with Labetalol Use: A Case Report with Systematic Review and Disproportionality Analysis Using FAERS. [PDF]

J Clin Pharmacol
Hendriksen ED, Rieder M, Urbantke E.
europepmc   +1 more source

Social Workers' Perceptions of Stakeholder Contributions to Regional Variation in the Numbers of ‘Care Orders at Home’ Being Recorded

Child &Family Social Work, EarlyView.
ABSTRACT This study builds on and extends the limited literature pertaining to the increasingly common care arrangement for children in England—the ‘Care Order at home’ [COAH]. Employing online focus groups and individual interviews, the study explores with 16 practising social workers their experience of COAH in both Northwest England and Greater ...
Ciarán Murphy
wiley   +1 more source