Results 171 to 180 of about 170,789 (315)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

[News Clip: Dallas Water Dispute in Court]

open access: yes, 1953
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a dispute over water treatment in the Dallas District ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Recognition Dispute As A “Trade Dispute” [PDF]

open access: yesThe Modern Law Review, 1960
openaire   +1 more source

Policy options for the management of territorial disputes in South-East Asia: A case study of the Preah Vihear temple dispute

open access: yes, 2013
The stability of the Southeast Asian region has been affected by a number of unresolved territorial and maritime disputes because most parts of the region were not demarcated after the colonial period.
Sattayarak, Tharita
core  

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