Results 51 to 60 of about 45,225 (304)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Australasian Dispute Resolution Journal: Past, Present and Future [PDF]

, 2023
The first edition of the Australasian Dispute Resolution Journal was published in February 1990. This article will recount its history and honour its founders and others who had the foresight to create a scholarly journal which has made and continues to ...
Spencer, David, Collins, Pauline
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluating Community Violence Intervention Programs: A Scoping Review Synthesizing Methods and Measures

Inquiry: The Journal of Health Care Organization, Provision, and Financing
Community violence intervention (CVI) is a promising strategy to reduce community violence, but research on CVI programs remains underdeveloped. While prior reviews have examined the effectiveness of certain CVI models, we lack a comprehensive synthesis ...
Meron Girma MPH, Julia Schleimer MPH, PhD, Astrid Aveledo MPA, Ayah Mustafa BA, Camerin Rencken MPH, PhD, Carolyn Thurston MA, Deepika Nehra MD, Kris Torset BA, Kristian Jones MA, PhD, Laura Johnson MSW, Lauren Polansky MLS, MPH, Olivia McCollum MPH, Orlando Ames AA, Rachel Ross MPH, Sam Decker MBA, Stephanie Taylor MPA, Tarrell Harrison BAS, Vivian Lyons MPH, PhD, Zaheed Lynch BA, Ali Rowhani-Rahbar MPH, MD, PhD   +19 more
doaj   +1 more source

Spain, and the Crisis of Investment Arbitration: Extra-EU Jurisdictions as Alternative enforcement Forums

Behavior & Law Journal
The purpose of this paper is to examine the structural crisis that currently faces the international investment arbitration regime within the European Union, with particular attention to the growing incompatibility between the Energy Charter Treaty (ECT)
Jesús Alfonso Soto Pineda, Evelyn Gacitúa, Fernando González, Elena Lucas   +3 more
doaj   +1 more source

Body‐Self Unity With a New Hip or Knee: Understanding Total Joint Replacement Within an Embodiment Framework

ACR Open Rheumatology, 2019
Medical research increasingly makes use of embodiment concepts to understand how illness disrupts unity of body and self. However, few have applied embodiment concepts in total joint replacement (TJR), an effective treatment for end‐stage arthritis.
Emma C. Lape, Pamela Hudak, Aileen M. Davis, Jeffrey N. Katz   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Apologies, Mediation and the Law: Resolution of Civil Disputes

Oñati Socio-Legal Series, 2016
Mediation is a process that provides opportunities for parties to civil disputes to engage in dialogue that can satisfy their expectations and needs for apologies.
Robyn Carroll, Alfred Allan, Margaret Halsmith   +2 more
doaj  

Judicial Dispute Resolution in Canada: Towards Accessible Dispute Resolution

The Windsor Yearbook of Access to Justice, 2018
This article argues that access to judges is an essential element of access to justice. Traditional civil litigation procedure aimed at preparation for trial that is complex, time-consuming and costly obstructs such access, especially for litigants ...
Archie Zariski
doaj   +1 more source