Results 81 to 90 of about 2,395,416 (349)

Alternative Dispute Resolution for Islamic Finance in Malaysia

open access: yes, 2018
The law lays down rules that govern private disputes, self-help actions or open-conflicts that may occur in the society. Here, courts, tribunals, arbitration and other dispute resolution forums are the main secular institutions in dispensing just ...
N. Khalidah Dahlan
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

La vertebració del règim espanyol de la mediació de consum en el marc del Dret europeu

open access: yesIDP, 2017
La resolució de litigis mitjançant de la mediació és una pràctica molt estesa entre les entitats espanyoles de resolució alternativa de litigis de consum, tant públiques com privades.
Fernando Esteban de la Rosa
doaj  

Blockchains and Online Dispute Resolution: Smart Contracts as an Alternative to Enforcement

open access: yes, 2016
As cross-border online transactions increase the issue of cross-border dispute resolution and enforcement becomes more and more topical. Disputes arising from ecommerce are seldom taken into the public courts and therefore online dispute resolution (ODR)
Anna Riikka Koulu
semanticscholar   +1 more source

Understanding IT for Dispute Resolution

open access: yesInternational Journal for Court Administration, 2011
Judges and judiciaries do not understand information technology (IT). This idea crops up quite often in discussions about IT for courts. The perceived slow rate of IT adoption in courts is explained by this lack of understanding. To my mind, this is not the main issue.
openaire   +4 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Can Artificial Intelligence and Online Dispute Resolution Enhance Efficiency and Effectiveness in Courts

open access: yes, 2017
The growing rise in the number of self-represented litigants has negative implications for both the court system and access to justice. The expanding use of Artificial Intelligence and the World Wide Web has led to the development and use of Online ...
John Zeleznikow
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

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