Results 121 to 130 of about 36,022 (292)
Are the humanities threatened by the increasing commercialisation of universities? [PDF]
As part of the Humanities Festival organised by the Faculty of Humanities & Social Sciences at Dublin City University in May 2006, a debate took place on the question of whether the humanities are threatened by the increasing commercialisation of ...
Sheehan, Helena
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Sex Differences and Promotion Prospects in Clinical Psychology in Scotland [PDF]
The following paper compares the gender bias in the Clinical Psychology profession in Scotland between 1990 and 1997. A larger proportion of females as compared with males are found both at the post-graduate training stage up until 1996 and at all levels
McKenzie, Karen, Murray, George
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Whose land was it anyway? The Crichel Down Rules and the sale of public land [PDF]
The guiding principle of compulsory purchase of interests in land in England and Wales is that of fairness, best stated in the words of Lord Justice Scott in Horn v Sunderland Corporation when he said that the owner has “the right to be put, so far as ...
Gibbard, Roger
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Christian Sacraments of Initiation: Baptism, Confirmation, Eucharist [PDF]
Reviewed Book: Osborne, Kenan B. The Christian Sacraments of Initiation: Baptism, Confirmation, Eucharist.
Weigel, Arnold D.
core +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Organ donation after euthanasia starting with anesthesia at home is legal in The Netherlands, Belgium, Canada and Spain. [PDF]
Mulder J, Sonneveld H.
europepmc +1 more source

