Results 101 to 110 of about 4,594 (295)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sites of Disquiet The Non-Space in Spanish American Short Narratives and Their Cinematic Transformations

open access: yes
Cover -- Copyright -- Contents -- Preface: Approaching Un-common Grounds -- Acknowledgments -- Introduction: Spotting the Non-Space -- Chapter One: Into Spatial Vagueness: Jorge Luis Borges's and Miguel Picazo's Hombre de la esquina rosada -- Chapter Two:
Kressner, Ilka.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

FERNANDO PESSOA READER OF PASCAL AND THE PROJECT OF THE BOOK OF DISQUIET

open access: yes, 2019
O presente artigo visa explorar as relações entre Pascal e Pessoa tendo por base o impacto da obra do autor francês tanto na estruturação quanto nas temáticas presentes ao longo do projeto do Livro do Desassossego. Com efeito, na Biblioteca Particular de
Souza, Cláudia, Ribeiro, Nuno
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Análise das Traduções em Chinês do Prefácio do “Livro do Desassossego” sob a Perspetiva da Teoria do Construal

open access: yesConfluenze
This article proposes a linguistic-textual analysis model inspired by the construal theory of Ronald W. Langacker, with its application in a study of four Chinese translations of the preface of the Book of Disquiet, posthumous work by Fernando Pessoa ...
Yujia Zhang
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

The trouble with the double: expressions of disquiet in and around law and literature

open access: yes, 2006
Talking, participating, engaging in the field of law and literature is an activity that causes me a lot of pleasure, indeed too much, even too painful a pleasure that easily tips over into, in one of the words in my title, disquiet, fear and anxiety.
Aristodemou, Maria
core  

Sites of Disquiet [PDF]

open access: yes, 2013
Some of the most important writers of the twentieth century, including Borges, Cortázar, Rulfo, and García Márquez, have explored ambiguous sites of a disquieting nature. Their characters face merging perspectives, deferral, darkness, or emptiness.
Kressner, Ilka
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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