Results 81 to 90 of about 5,793 (279)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
El Nuevo Livro do Desassossego de Jerónimo Pizarro
MatLit, 2014 Review of Jerónimo Pizarro, Livro do Desassossego, Lisboa, Edição Tinta-da-china, 2013, 607 pp.
Diego Giménez
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Fragmentación y Edición en el Libro del Desasosiego
MatLit, 2013 This article argues that the various editions of the Book of Disquiet represent some defacement. The editor makes decisions that the writer did not take on textual variables and selection of fragments. In modernity the "book" emerges as a utopian horizon.
Diego Giménez
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
From The Heteronymic Potential of Mark Amerika
Texto DigitalAll of the writing contained here is excerpted from a longer work of narrative art, one that totals ten experimental books created by slightly altering the text outputs of various GPT programs.
Mark Amerika
doaj +1 more source
«No one else can make you change». Formazione, giovinezza, musica, a partire dal Sessantotto
Studi sulla Formazione, 2019 Beyond the number of stereotypes concerning 1968, in that year the intersection between youth and music achieved a full-fledged Bildungsroman that recovered the poetry of disquiet as powerful tool for relief and self-affirmation, for modelling/transfer ...
Elena Madrussan
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Osgoode Hall Law Journal, 1991 The received wisdom is that an idea as such is not legally protected. But now courts are embarking on a course which, at least in some respects, embraces the proposition that ideas will sometimes be protected.
Grant Hammond
doaj +1 more source