Results 71 to 80 of about 4,594 (295)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Reorientacje. Studia nad męskościami a literatura polska ostatniego stulecia
Teksty Drugie, 2023 The article presents Wojciech Śmieja’s literary studies on masculinities in the Polish twentieth and twenty-first centuries literature, especially focusing on Śmieja’s book Nie/podległości i transformacje.
Tomasz Tomasik
doaj
, 2016 Michel van der Aa’s music theatre work, The Book of Disquiet, was the first staged production in Linz’s Cultural Capital of Europe celebrations in January 2009. Following his opera After Life, which enjoyed a sell-out run at the Holland Festival in 2006,
Office of Arts + Cultural Programming +1 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Challenging Modernism: Fernando Pessoa and the Book of Disquiet
, 2013 In this thesis I studied the Book of Disquiet by Portuguese author Fernando Pessoa (1888-1935) in order to determine to what extent the work could be linked to European literary modernism.
Dep Talen, Literatuur en Communicatie +2 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
TEI4LdoD: Textual Encoding and Social Editing in Web 2.0 Environments
Journal of the Text Encoding Initiative, 2015 In this article we describe how textual encoding is used in our current project of constructing a digital archive of Fernando Pessoa’s Livro do Desassossego [LdoD]. Our model for virtualizing the authorial and editorial forms of this unfinished work aims
António Rito Silva, Manuel Portela
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source