Results 91 to 100 of about 885,017 (286)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Editorial: Business and Information Management Realities in a World of Global Disruption and 4IR

African Journal of Inter-Multidisciplinary Studies
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Trisha Ramsuraj, Peggy Mthalane
doaj   +1 more source

Developing a Model for Solving the Flight Perturbation Problem

Journal of Airline and Airport Management, 2015
Purpose: In the aviation and airline industry, crew costs are the second largest direct operating cost next to the fuel costs. But unlike the fuel costs, a considerable portion of the crew costs can be saved through optimized utilization of the internal ...
Amirreza Nickkar, Seyedmohammad Seyed-Hosseini, Hassan Javanshir, Hasan Khaksar   +3 more
doaj   +1 more source

Algorithmic Support for Railway Disruption Management [PDF]

Disruptions of a railway system are responsible for longer travel times and much discomfort for the passengers. Since disruptions are inevitable, the railway system should be prepared to deal with them effectively.
Huisman, D., Kroon, L.G.
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Disruption Management in Passenger Railway Transportation [PDF]

, 2009
This paper deals with disruption management in passenger railway transportation. In the disruption management process, many actors belonging to different organizations play a role. In this paper we therefore describe the process itself and the roles of the different actors.
Jespersen-Groth, J., Potthoff, D., Clausen, J., Huisman, D., Kroon, L.G., Maróti, G., Nielsen, M.N.   +6 more
openaire   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Influence of Marketing Strategy on Marketing Performance from a Management Perspective in the Disruption Era

Binus Business Review
The world continues to develop and change, and everything is digital-based in the current era of disruption. The retail industry is one of the business sectors most severely impacted by the COVID-19 pandemic and the disruption era.
I Gusti Ngurah Satria Wijaya, Annisa Balqis Bashira Syahrir Malintang Latanro, Ni Nyoman Arie Rahayu Sugianitri   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Exploring Vietnamese logistics service quality in the run up to AEC 2015 [PDF]

Paper presented at the 7th International Conference on Logistics and Transport, 17th to 20th November, Lyon, France. Abstract: The logistics and supply chain management domain faces a number of ongoing trends and resultant challenges including costs, the
Grant, David, Huong, Trinh Thi Thu
core