Results 71 to 80 of about 351,595 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Efficacy of Positivist Parenting Method Training on Disruptive, Destructive and Self-Control Behaviors in Fifth-Grade Primary School Female Students [PDF]
پژوهشهای کاربردی روانشناختیThe present study was conducted to investigate efficacy of positivist parenting method training on disruptive, destructive, and self-control behaviors among female students in fifth-grade primary school. It was quasi-experimental study with control group
Vahideh Azimi +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
What Can Be Done About A Disruptive Physician? A Legal Analysis [PDF]
, 2020 House, a medical drama about an infectious disease specialist, entertained television audiences for years as the irascible and pill-popping physician solved medical mysteries with the zeal of a modern-day Sherlock Holmes while playing mind games with his
Hodge, Samuel D., Jr.
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Youth Academic Success:It Starts in the Home [PDF]
, 2020 Academic Success of youth is critical for their future success as well as for the economic and social health of their communities. Using a mixed methods approach (the 2008-2013 “Social Capital and Children’s Development” survey and commentaries of eight ...
Ybarra, Veronica Fay
core +1 more source
The motivating operation and negatively reinforced problem behavior. A systematic review. [PDF]
, 2014 The concept of motivational operations exerts an increasing influence on the understanding and assessment of problem behavior in people with intellectual and developmental disability. In this systematic review of 59 methodologically robust studies of the
Borthwick-Duffy S. A. +7 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Acta PsychologicaObjective: Disruptive classroom behavior in physical education classes is a common challenge in classroom management. Teachers often respond to such behavior with criticism; however, different types of criticism may produce distinct behavioral responses ...
Jing Bai, Kai Huang, Yingchen Bi
doaj +1 more source