Results 51 to 60 of about 6,646,090 (317)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Suubi4StrongerFamilies: A study protocol for a clustered randomized clinical trial addressing child behavioral health by strengthening financial stability and parenting among families in Uganda

Frontiers in Psychiatry, 2022
BackgroundChildren in Sub-Saharan Africa are burdened by significant unmet mental health needs. Across the region, high rates of poverty, HIV/AIDS, food insecurity, stigma, and an inadequate health safety net system exacerbate serious child behavioral ...
Fred M. Ssewamala, Mary M. McKay, Ozge Sensoy Bahar, Proscovia Nabunya, Torsten Neilands, Joshua Kiyingi, Phionah Namatovu, Shenyang Guo, Noeline Nakasujja, Abel Mwebembezi   +9 more
doaj   +1 more source

Preschoolers’ free play : connections with emotional and social functioning [PDF]

, 2016
Play has an important role in various aspects of children’s development. However, time for free play has declined substantially over the last decades.
Neto, Carlos, Rieffe, Carolien, Veiga, Guida   +2 more
core   +2 more sources

Dementia Caregiver Burden: A Research Update and Critical Analysis [PDF]

, 2017
Purpose of Review: This article provides an updated review of the determinants of caregiver burden and depression, with a focus on care demands and especially the differential effects of various neuropsychiatric symptoms or symptom clusters.
A Brioschi Guevara, AB Sallim, AL Harmell, Alzheimer’s Disease International, AN Leggett, BT Mausbach, C Boutoleau-Bretonnière, C Wong, CC Wong, CG Lyketsos, CW Zhu, D Aarsland, D Craig, DI Kaufer, DM Bass, DR Lee, E Mioshi, E Svendsboe, EB Fauth, EB Fauth, G D’Onofrio, G Spalletta, HS Kang, J Bang, J Garre-Olmo, J Garre-Olmo, J Georges, J Liu, J Merrilees, J Savla, J Savla, J Vilalta-Franch, JC Mourik, JE Gaugler, JE Gaugler, JE Gaugler, JE Gaugler, JE Gaugler, JL Givens, JM Haro, K Eska, K Ornstein, KA Ornstein, KJ Joling, L Massimo, L Teri, LI Pearlin, M Park, M Pinquart, M Pinquart, ME Vugt de, ME Vugt de, N Hasegawa, PH Robert, RJ Perry, S Gauthier, S Hsieh, S Huang, S-T Cheng, S-T Cheng, S-T Cheng, S-T Cheng, SA Khoo, SH Shim, SH Zarit, Sheung-Tak Cheng, SK Roepke, TB Hughes, TJ Richardson, TL Patterson, V Dauphinot, World Health Organization, Y Oh, Z Walker   +73 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The MHD Kelvin-Helmholtz Instability III: The Role of Sheared Magnetic Field in Planar Flows [PDF]

, 1999
We have carried out simulations of the nonlinear evolution of the magnetohydrodynamic (MHD) Kelvin-Helmholtz (KH) instability for compressible fluids in $2\frac{1}{2}$-dimensions, extending our previous work by Frank et al (1996) and Jones \etal (1997 ...
Adam Frank, Bodo G., Dongsu Ryu, Ferrari A., Hyunju Jeong, Miura A., Miura A., Miura A., Sytine I. V., T. W. Jones, Weiss N. O., Wu C. C.   +11 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source