Results 91 to 100 of about 6,614 (249)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Isthmohyla zeteki [PDF]

open access: yes, 2006
Number of Pages: 3Integrative BiologyGeological ...
Gerald, Gary W.
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Conspicuous male coloration impairs survival against avian predators in Aegean wall lizards, Podarcis erhardii. [PDF]

open access: yes, 2015
This is the final version of the article. It first appeared from Wiley via http://dx.doi.org/10.1002/ece3.1650Animal coloration is strikingly diverse in nature.
Marshall, Kate LA   +2 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Discriminative context-aware network for camouflaged object detection

open access: yesFrontiers in Artificial Intelligence
IntroductionAnimals use camouflage (background matching, disruptive coloration, etc.) for protection, confusing predators and making detection difficult.
Chidiebere Somadina Ike   +4 more
doaj   +1 more source

Nature as paradigm for sustainability in the textile and apparel industry [PDF]

open access: yes, 2012
Imagine if clothing of the future would adapt, grow, self repair and change appearance. The relationship between wearer and garment would be that of symbiosis enabled by developments in material science that produce textiles able to imitate ...
Kapsali, Veronika
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Phenotype-environment matching and colour change for camouflage in the shore crab Carcinus maenas [PDF]

open access: yes, 2016
Camouflage is one of the most common antipredator defences found in nature (Ruxton et al., 2004). The shore crab Carcinus maenas is vulnerable to attack by shore birds, fish species and even other crabs.. C.
Easley, Jennifer Lauren
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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