We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham +11 more
wiley +1 more source
Green Synthesis of ZnSe Nanoparticles via Laser Fragmentation: Effect of Laser Pulse Energy on Nanoparticle Size and Surface Phonon Modes. [PDF]
Maldonado-Altamirano P +4 more
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph +11 more
wiley +1 more source
Fading on the beach: pigmentation plasticity adjusts coloration to substrate type in coastal Western spadefoot toads. [PDF]
Lorrain-Soligon L +5 more
europepmc +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Analysis of Interactions Between Pyomelanin and the Extracellular Matrix in an Ex Vivo Turkey Tendon Model. [PDF]
Shepherd RF +11 more
europepmc +1 more source
Microalgae Techno-Functional Properties in Bread, Cookies, and Pasta Products: A Review. [PDF]
Atubukha B +5 more
europepmc +1 more source
Genome-wide association study in a lettuce core collection from 811 accessions reveals genetic loci for anthocyanin accumulation and cultivar development. [PDF]
Huo G +12 more
europepmc +1 more source

