Results 61 to 70 of about 124,123 (223)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Perceptions of carotenoid and melanin colouration in faces among young Australian adults [PDF]
, 2018 Objective: Human skin colour is influenced by three pigments: haemoglobin, carotenoids, and melanin. Carotenoids are abundant in fruits and vegetables, and when consumed accumulate in all layers of the skin, predominantly imparting yellowness (b*). This
Hutchesson, Melinda J. +17 more
core +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Exploring the Disruptive Nature of Disruptive Technology
, 2009 Christensen's ideas on disruptive technology (DT) have undergone much debate in mainstream strategy and innovation literature, largely concerning the difficulties in their application. The main issue seems to be the paradox of encouraging the development
Pilkington, A.
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Colour counts: Effects of aposematic colouration in chick learning
, 2007 Much has been written about the effects of bead colour and sheen on the consolidation of one-trial passive avoidance learning tasks in day-old chicks. Laboratories have adopted a variety of training procedures using beads of varying sizes, colours and ...
Burne, Thomas, Johnston, Amy
core
Structural colouration in blow flies [PDF]
peer reviewedStructural colours in nature arise from intricate photonic architectures that produce often vivid and iridescent appearances. These colours are generated by physical interactions of light with nanostructures rather than pigments, often ...
Vukusic, Pete +4 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Measurements of colouration, distribution, unpalatability, and predation
, 2017 Measurements of colouration, distribution, unpalatability for 100 mimics and estimates of predation in the ...
Lenka Petráková (5717912) +9 more
core +1 more source