Results 91 to 100 of about 1,215,713 (372)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Morphological variability of the leg muscles: potential pitfalls on ultrasound that await clinicians
Folia MorphologicaBACKGROUND: Although muscles and their tendons are not considered the most morphologically variable structures, they still manifest a substantial diversity of variants.
Marta Pośnik +4 more
doaj +1 more source
European Journal of Breast Health, 2021 Objective:Neo-adjuvant chemotherapy (NAC) is the treatment of choice for patients with locally advanced breast cancer (BC). In luminal-like BC, the decision to administer NAC remains controversial.
Erika Barbieri +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]
, 2018 There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin +12 more
core +1 more source
Dissecting hydrophobicity [PDF]
Proceedings of the National Academy of Sciences, 2007 The perceived phobia (fear) of some apolar substances for aqueous (hydro) environments does not imply lack of attraction to water. Rather, it originates from the strength of this attraction, which, similar to that between the constituents of apolar substances, is smaller than the force between water molecules.
openaire +3 more sources
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Folia MorphologicaThe iliopsoas muscle complex traditionally consists of the iliacus muscle and psoas major, occasionally including the psoas minor. These elements were distinguished based on their shared function and common distal attachment.
Marta Pośnik +4 more
doaj +1 more source
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.
JCI Insight, 2018 Proteoglycan accumulation is a hallmark of medial degeneration in thoracic aortic aneurysm and dissection (TAAD). Here, we defined the aortic proteoglycanome using mass spectrometry, and based on the findings, investigated the large aggregating ...
Frank S. Cikach +10 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source