Results 101 to 110 of about 638,530 (307)

Ascending thoracic aorta dimension and outcomes in acute type B dissection (from the International Registry of Acute Aortic Dissection [IRAD])

open access: yes, 2011
It is not well known if the size of the ascending thoracic aorta at presentation predicts features of presentation, management, and outcomes in patients with acute type B aortic dissection.
J. B. Froehlich   +44 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Temporalis muscle flap in craniofacial reconstruction: anatomy, techniques, outcomes, and innovations

open access: yesFrontiers in Surgery
BackgroundThe temporalis muscle flap (TMF) remains an essential reconstructive option in contemporary craniofacial reconstructive surgery (CRS) owing to its reliable vascularity, anatomical proximity to common defect areas, and substantial soft tissue ...
Ingrid C. Landfald   +5 more
doaj   +1 more source

Dissecting hydrophobicity [PDF]

open access: yesProceedings of the National Academy of Sciences, 2007
The perceived phobia (fear) of some apolar substances for aqueous (hydro) environments does not imply lack of attraction to water. Rather, it originates from the strength of this attraction, which, similar to that between the constituents of apolar substances, is smaller than the force between water molecules.
openaire   +2 more sources

A comparison between traditional dissection and digital dissection.

open access: yes, 2015
Mean muscle weights of the left and right side from the gross dissection of specimen 3, and muscle volumes from the MRI digital dissection of the same specimen, including percentages for each muscle.A comparison between traditional dissection and digital
Peter W. Trusler (695091)   +1 more
core   +1 more source

Bilateral chylothorax following neck dissection: a case report. [PDF]

open access: yes, 2014
BACKGROUND Chylothorax is an extremely rare but potentially life-threatening complication after radical neck dissection. We report the case of a bilateral chylothorax after total thyroidectomy and cervico-central and cervico-lateral lymphadenectomy ...
Candinas, Daniel   +11 more
core   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Comparative Study between Cold Dissection and Bipolar Diathermy Dissection Methods of Tonsillectomy [PDF]

open access: yes, 2020
A comparative study between two methods of tonsillectomy - Cold Dissection and Bipolar Diathermy Dissection was conducted in 60 patients. The parameters for comparison were duration of the surgical technique, tonsillectomy associated haemorrhage and post-
Singh, Oinam Priyokumar   +5 more
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

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