Results 121 to 130 of about 288,431 (247)
Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim +10 more
wiley +1 more source
Thoracic Aortic Dissection and Thoracoabdominal Acute Type B Aortic Dissections Have Superior Survival When Treated With Thoracic Endovascular Aneurysm Repair and Open Surgery Compared to Medical Therapy: Outcomes from the National Medicare Database [PDF]
James F. McKinsey +4 more
openalex +1 more source
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain +5 more
wiley +1 more source
Dissection of the ascending thoracic aorta as a complication of percutaneous coronary intervention
Cihangir Uyan, Huseyin Arinc, Huseyin Gunduz, Ramazan AkdemirAbant izzet Baysal University, izzet Baysal Medical Faculty, Cardiology Department, 14280 Golkoy, Bolu, TurkeyAbstract: Acute aortic dissection is a medical emergency with high morbidity and ...
Cihangir Uyan +3 more
doaj
It is a medical emergency! Act fast: a case report of painless aortic dissection [PDF]
Anusha Yanamadala +2 more
openalex +1 more source
A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico +8 more
wiley +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source

