Possible role of extracellularly released phagocytic proteinases in the coagulation disorder during liver transplantation [PDF]
Orthotopic liver transplantation is frequently associated with a complex coagulation disorder, influencing the outcome of the procedure. In this respect, disseminated intravascular coagulation (DIC) had been suggested to be of causative importance for ...
Blumhardt, G. +6 more
core
Antimicrobial prescribing guidelines for horses in Australia
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt +18 more
wiley +1 more source
Synthetic cathinones related fatalities: an update [PDF]
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P. +5 more
core +1 more source
Predictors of response to emergent therapies in paediatric immune thrombocytopenia
Emergent therapies (ET), which include intravenous immunoglobulin (IVIG), corticosteroids and intravenous anti‐Rho(D) immunoglobulin, are used to treat acute episodes of bleeding in children with immune thrombocytopenia (ITP). Through comparison of clinical characteristics in paediatric patients with ITP responsive to ET versus those non‐responsive to ...
Candelaria O'Farrell +7 more
wiley +1 more source
Disseminated Intravascular Coagulation pada Cedera Otak Traumatik
Disseminated Intravascular Coagulation (DIC) merupakan konsekuensi yang sering dan penting pada cedera otak traumatik (Traumatic Brain Injury/TBI) dan menyebabkan cedera otak sekunder.
Agus Baratha Suyasa +2 more
doaj +1 more source
Disseminated intravascular coagulation [PDF]
‘Disseminated intravascular coagulation (DIC)’ occurs commonly in critical illnesses such as sepsis, trauma, cancer, and complications of surgery and pregnancy. Mortality is very high.
Chang, Jae C
core +1 more source
Abstract Background Viscoelastic coagulation testing (VCT) identifies subclinical disruption of coagulation homeostasis and may improve prognostication, particularly for patients with severe systemic inflammation or shock. Machine learning (ML) algorithms may capture complex relationships between clinical variables better than linear regression (GLM ...
Brandi M. Macleod +3 more
wiley +1 more source
Chronic Disseminated Intravascular Coagulation: A Case Report
In health there is a balance between the coagulation and anti-coagulation systems, but in disseminated intravascular coagulation (DIC) the coagulation mechanism is activated inappropriately and in a diffuse way.
Md Abul Kalam Azad +3 more
doaj +1 more source
Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]
Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA +5 more
core +1 more source
Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis +2 more
wiley +1 more source

