Results 151 to 160 of about 313,747 (258)

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, Volume 13, Issue 55, 5 October 2026.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Lupus anticoagulant and protein S deficiency in a child who developed disseminated intravascular coagulation in association with varicella

The Turkish Journal of Pediatrics, 2001
Varicella is not always a benign disease it may cause serious complications. We report a two-year-old boy with disseminated intravascular coagulation in association with varicella.
Z Kurugöl, F Vardar, F Ozkinay, K Kavakli, B Cetinkaya, C Ozkinay   +5 more
doaj  

Cardiovascular Toxicity Associated With Bispecific Antibodies in Hematological Malignancies: A Comprehensive Pharmacovigilance Analysis

American Journal of Hematology, Volume 101, Issue 10, Page 2546-2556, October 2026.
ABSTRACT Cardiovascular adverse events (CVAEs) associated with bispecific T‐cell engaging antibodies (BsAbs) have not been systematically investigated across approved agents. In this disproportionality analysis of FAERS (December 2014–September 2025), reports listing BsAbs as the primary suspected drug (n = 7647) were compared with all other drugs in ...
Malak Munir, Ahmed Sayed, Dae Hyun Lee, Sanam Ghazi, Mustafa M. Houmsse, Saad Badat, Abdul Moeed, Avirup Guha, Daniel Addison, Narendranath Epperla   +9 more
wiley   +1 more source

Clinical outcomes of placenta accreta spectrum in a Tunisian referral maternity unit: A retrospective review

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 1045-1047, November 2026.
Hannachi Mohammed Amine, Samaali Khaoula, Zangar Salim, Somri Bilel, Hkiri Takwa, Ben Amor Feriel, Ben Aziza Rim, Ben Marzouk Sofiane, Kacem Samia, Malek Monia, Neji Khaled   +10 more
wiley   +1 more source

Incidence, Clinical Characteristics, Management, and Outcomes of Hematologic Immune‐Related Adverse Events Associated With Immune Checkpoint Inhibitors: A Single‐Center Japanese Retrospective Cohort Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
This single‐center retrospective study evaluated hematologic immune‐related adverse events (irAEs) among 3371 patients treated with immune checkpoint inhibitors. Forty patients developed hematologic irAEs (1.2%); 85.0% of events were Grade 3 or higher, and the median time to onset was 12 weeks.
Ryo Yoshimaru, Hirotaka Nakamura, Yong‐Mei Guo, Kensuke Matsuda, Tetsuya Sakai, Yoshitaka Zenke, Kiyotaka Yoh, Kohei Shitara, Nobuaki Matsubara, Kenichi Harano, Hiromichi Nakajima, Nobuyuki Takahashi, Masafumi Ikeda, Takao Fujisawa, Saki Nakamura, Kenta Akie, Masayuki Ito, Masashi Wakabayashi, Junichiro Yuda   +18 more
wiley   +1 more source

Scrub Typhus Meningoencephalitis With Concurrent Brucellosis in Rural Nepal: Diagnostic Challenges With Negative PCR in a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 10, October 2026.
Scrub typhus meningoencephalitis with concurrent Brucellosis. ABSTRACT Scrub typhus is an important cause of acute febrile illness in Nepal and can rarely present with meningoencephalitis and multiorgan involvement. We report a 32‐year‐old female farmer from rural Nepal who presented during the monsoon season with high‐grade fever, myalgia, vomiting ...
Pashupati Pokharel, Diwash Rai, Milan Bajracharya, Abhikshya Basnet, Bimal Sharma Chalise, Arati Baskota, Andrew B. Trotter   +6 more
wiley   +1 more source

Potential Benefit of Ruxolitinib in Suspected Ocular and Neurological Transplant‐Associated Thrombotic Microangiopathy After Allogeneic Stem Cell Transplantation: A Case Report and Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT We describe a rare case of suspected delayed‐onset TA‐TMA with ocular and neurological involvement following allo‐HSCT. The condition was refractory to standard therapies; neurological improvement was temporally associated with ruxolitinib initiation, suggesting a possible GVHD overlap.
Lise‐Marie Pillet, Antoine Arandilla, Gaëtan Sauvetre, Paul Goupillou, Adrien Lefevre, Maximilien Grall, Antoine Bonnevalle, Bertrand Bourre, Dominique Penther, Sophie Porcheron, Fabrice Jardin, Mustafa Alani, Sydney Dubois, Vincent Camus   +13 more
wiley   +1 more source

Cancer‐Related Microangiopathic Haemolytic Anemia Revealing Occult Metastatic Gastrointestinal Signet‐Ring Cell Carcinoma: A Clinicopathological Case Report and Practical Differential Diagnostic Approach

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case highlights key laboratory red flags and a failure to respond to standard treatment, both of which should prompt urgent investigation for occult malignancy in patients presenting with cancer‐related microangiopathic hemolytic anemia (CR‐MAHA).
Danijela Jovanovic, Snezana Sretenovic, Dalibor Jovanovic, Milena Ilic, Predrag Djurdjevic   +4 more
wiley   +1 more source

Hong Kong Poison Information Centre: Annual report 2022

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2022.
Tin Yat Anthony Chow, Chi Keung Chan, Shan Liu, Sze Hong Ng, Man Li Tse   +4 more
wiley   +1 more source

Disseminated intravascular coagulation in pregnancy: insights from an international collaborative registry. [PDF]

J Thromb Haemost
Federspiel JJ, Berkowitz C, Lim G.
europepmc   +1 more source