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Disseminated Intravascular Coagulation
Emergency Medicine Clinics of North America, 1993DIC is a consumptive thrombohemorrhagic life-threatening disorder resulting in multiple coagulation, platelet, and fibrinolytic abnormalities. The causes are legion. Diagnosis is both clinical and laboratory based. Therapy remains controversial and should be based on clinical presentation, although some clinical syndromes may allow for specific ...
Ricciardetto P. Scalzi, James A. Gilbert
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Disseminated Intravascular Coagulation
Transfusion, 1977Current concepts of the etiology, pathophysiology, clinical and laboratory diagnosis, and management of fulminant and low-grade DIC have been presented. Considerable attention has been devoted to interrelationships within the hemostasis system. Only by clearly understanding these pathophysiologic interrelationships can the clinician and laboratory ...
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Disseminated Intravascular Coagulation in Cancer: An Update
Seminars in Thrombosis and Hemostasis, 2019Cancer often leads to the activation of coagulation, manifesting as disseminated intravascular coagulation (DIC) in its most extreme form. DIC is characterized by systemic intravascular coagulation activation (leading to deposition of intravascular ...
M. Levi
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Disseminated intravascular coagulation
Acta Anaesthesiologica Scandinavica, 1991This review encompasses a description of the main pathophysiological events leading to disseminated intravascular coagulation (DIC). Emphasis has been put on microcirculatory disturbances and endothelial dysfunction. The normal hemostatic functions of the vascular endothelium are described.
Elsa Eriksson +2 more
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Disseminated intravascular coagulation: an update on pathogenesis and diagnosis
Expert Review of Hematology, 2018Introduction: Activation of the hemostatic system can occur in many clinical conditions. However, a systemic and strong activation of coagulation complicating clinical settings such as sepsis, trauma or malignant disease may result in the occurrence ...
M. Levi, S. Sivapalaratnam
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Disseminated intravascular coagulation
Best Practice & Research Clinical Obstetrics & Gynaecology, 2001Healthy pregnancy is accompanied by changes in the haemostatic system which convert it into a hypercoagulable state vulnerable to a spectrum of disorders ranging from venous thromboembolism to disseminated intravascular coagulation (DIC). This latter is always a secondary phenomenon triggered by specific disorders such as abruptio placentae and ...
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Disseminated Intravascular Coagulation
Veterinary Clinics of North America: Small Animal Practice, 1988Etiology, pathogenesis, clinical features, laboratory findings, and therapy of disseminated intravascular coagulation (DIC) in the dog and the cat are reviewed.
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Disseminated intravascular coagulation
Current Opinion in Hematology, 1995Disseminated intravascular coagulation is the result of a severe underlying disorder that initiates massive activation of the coagulation system. It is always a symptom of the underlying disorder. These disorders may be as varied as meningococcemia and abdominal aortic aneurysm. Disseminated intravascular coagulation is a clinical diagnosis.
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Thromboelastometry in critically ill patients with disseminated intravascular coagulation.
Blood Coagulation and Fibrinolysis, 2019: Coagulopathy has a high incidence in critically ill patients and is often caused by disseminated intravascular coagulation (DIC). Although the clinical picture of DIC ranges from a prothrombotic state to severe consumption coagulopathy with an ...
M. C. Müller +4 more
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Disseminated Intravascular Coagulation
1978Disseminated intravascular coagulation (DIC) is a new concept in the etiology of disease [3]. It is defined as acute, transient coagulation occurring in the flowing blood throughout the vascular tree which may obstruct the microcirculation. It may or may not result in an accumulation of fibrin but does involve the transformation of fibrinogen into ...
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