Results 71 to 80 of about 93,838 (342)

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

Exploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye, Wenhua Huang, Shujuan Yu, Yan Guo, Peng Sun, Ziyuan Chen, Linhui Hao, Yan Zhang, Caixia Li, Yongqiang Jiang, Jun Wu, Li Zhu, Hengliang Wang, Chao Pan   +13 more
wiley   +1 more source

Effect of the administration of recombinant hirudin and/or tissue-plasminogen activator (t-PA) on endotoxin-induced disseminated intravascular coagulation model in rabbits [PDF]

, 1999
We evaluated the effect of r-hirudin and/or tissue-plasminogen activator (t-PA) in a model of DIC in rabbits induced by i.v. infusion of 100 micrograms/kg/h/6 h endotoxin. Rabbits were treated with saline (endotoxin control group), r-hirudin at 0.3 mg/kg/
Hermida, J. (José), Montes, R. (Ramón), Muñoz, M.C. (María Carmen), Orbe, J. (Josune), Paramo, J.A. (José Antonio), Rocha, E. (Eduardo)   +5 more
core   +1 more source

Does induction or augmentation of labor increase the risk of postpartum hemorrhage in pregnant women with anemia? A multicenter prospective cohort study in India

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 299-309, April 2025.
Abstract Objective To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.
Tuck Seng Cheng, Farzana Zahir, Carolin Solomi V, Ashok Verma, Sereesha Rao, Saswati Sanyal Choudhury, Gitanjali Deka, Pranabika Mahanta, Swapna Kakoty, Robin Medhi, Shakuntala Chhabra, Anjali Rani, Amrit Bora, Indrani Roy, Bina Minz, Omesh Kumar Bharti, Rupanjali Deka, Charles Opondo, David Churchill, Marian Knight, Jennifer J. Kurinczuk, Manisha Nair   +21 more
wiley   +1 more source

Effect of CMF-chemotherapy on blood coagulation in patients with breast cancer [PDF]

, 2002
BACKGROUND: Influences of CMF (cyclophosphamide, methotrexate,5-fluorouracil) chemotherapy on blood coagulation were investigated in 30 patients receiving adjuvant chemotherapy and in 30 patients receiving chemotherapy for metastatic breast cancer ...
Petrović Dragana
core   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Koagulasi Intravasa Diseminata [PDF]

, 1991
Suhardi D. A. &A. H. Asdie - Disseminated intravascular coagulation Bleeding may result from abnormalities\u27 of platelet, blood vessel walls, or coagulation.
Suhardi D. A dan Ahmad H. Asdie
core   +1 more source

Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation [PDF]

, 1985
The blood coagulation system of 66 consecutive patients undergoing consecutive liver transplantations was monitored by thrombelastograph and analytic coagulation profile.
Bontempo, FA, Kang, YG, Lewis, JH, Marquez, J, Martin, DJ, Shaw, BW, Starzl, TE, Winter, PM   +7 more
core   +1 more source

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

Serum Circ‐DLGAP4 and miR‐9 as Potential Biomarkers in Pancreatic Cancer

Journal of Clinical Laboratory Analysis, EarlyView.
Pancreatic cancer remains one of the malignancies characterized by the most insidious onset and dire prognosis. Preliminary diagnostic biomarkers are essential for timely identification and improved prognosis. Circ‐DLGAP4 and miR‐109 are intriguing, easily accessible genetic indicators for numerous diseases.
Marwa A. Ali, Olfat G. Shaker, Eman M. Ezzat, Mohamed Saad Zaghloul Ahmed, Shimaa Mohammed Elasmer, Marwa Mamdouh Ahmed Abdelhafeez, Mohamed Zaidan, Raghda Yahia Abu El‐Ela, Marwa N. AbdelHafez, Eman Fares, Ahmad A. Al Abdulqader, Aeshah A. Awaji, Mariam K. Alamoudi, Omayma O. Abdelaleem   +13 more
wiley   +1 more source