Results 111 to 120 of about 569,475 (298)

Disseminated Metacestode Versteria Species Infection in Woman, Pennsylvania, USA1 [PDF]

, 2019
Bethany Lehman, Sixto M. Leal, Gary W. Procop, Elise M. O’Connell, Jahangheer Shaik, Theodore E. Nash, Thomas B. Nutman, Stephen Jones, Stephanie Braunthal, Shetal N. Shah, Michael Cruise, Sanjay Mukhopadhyay, Jona Banzon   +12 more
openalex   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The clinical effectiveness of trastuzumab for breast cancer: a systematic review

Health Technology Assessment, 2002
R. Lewis, A.-.M Bagnall, C. Forbes, E. Shirran, S. Duffy, J. Kleijnen, R. Riemsma, G. ter Riet   +7 more
doaj   +1 more source

Time and Frequency Transfer and Dissemination Methods Using Optical Fiber Network

, 2006
M. Amemiya, Michito Imae, Yasuhisa Fujii, Tomonari Suzuyama, Shinichi Ohshima, Shin-ichi Aoyagi, Yoshihiro Takigawa, Masami Kihara   +7 more
openalex   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Novel Granule-Based Formulation as a Health Supplement With an Extended Shelf Life, Derived From the Pulp of Bael (Aegle marmelos) and Various Herbs

Journal of Food Quality
Bael (Aegle marmelos L. Correa) is a fruit known for its historical significance and contains nutritional and medicinal properties. It is a good source of essential vitamins and minerals to maintain human health.
Vipin Kumar, Priyanka Singh, Sanjay Pathak, Sanjay Kumar, Ramesh Kumar Srivastava   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis

Health Technology Assessment
Background Proliferative diabetic retinopathy is a major cause of sight loss in people with diabetes, with a high risk of vitreous haemorrhage, tractional retinal detachment and other complications.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, João Pereira Figueira, Sobha Sivaprasad, John G Lawrenson, Tunde Peto, David Steel   +14 more
doaj   +1 more source

Investigation and Evaluation of Chinese Clinical Practice Guidelines Published in Medical Journals in 2019: Analysis on Dissemination and Implementation

, 2022
LYU Meng, Xufei Luo, Yunlan Liu, Mengjuan Ren, Xiao Liu, Qianling Shi, Zijun Wang, LU Shuya, Hui Liu, Qiu Li, Yaolong Chen   +10 more
openalex   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source