Results 121 to 130 of about 448,663 (255)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis

open access: yesHealth Technology Assessment
Background Diabetic retinopathy is a major cause of sight loss in people with diabetes. The most severe form, proliferative diabetic retinopathy, carries a high risk of vision loss, vitreous haemorrhage, macular oedema and other harms.
Mark Simmonds   +12 more
doaj   +1 more source

Bean Technology Dissemination Project Beneficiary Survey in Honduras

open access: yes
To address the critical shortage of high quality bean seed that smallholder resource poor farmers need to increase productivity, in 2010, the Dry Grain Pulses CRSP managed by Michigan State University, through funding from USAID, initiated the Bean ...
Maredia, Mywish
core   +1 more source

Using research to inform health policy: barriers and strategies in developing countries

open access: yes, 2004
This article examines the dissemination and uptake of health research into policy and program delivery in four developing countries. In-depth interviews were conducted with health researchers, policymakers, and practitioners at both the local and ...
Hennink, Monique   +4 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The clinical effectiveness of trastuzumab for breast cancer: a systematic review

open access: yesHealth Technology Assessment, 2002
R. Lewis   +7 more
doaj   +1 more source

A Novel Granule-Based Formulation as a Health Supplement With an Extended Shelf Life, Derived From the Pulp of Bael (Aegle marmelos) and Various Herbs

open access: yesJournal of Food Quality
Bael (Aegle marmelos L. Correa) is a fruit known for its historical significance and contains nutritional and medicinal properties. It is a good source of essential vitamins and minerals to maintain human health.
Vipin Kumar   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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