Results 121 to 130 of about 874,152 (294)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis

Health Technology Assessment
Background Proliferative diabetic retinopathy is a major cause of sight loss in people with diabetes, with a high risk of vitreous haemorrhage, tractional retinal detachment and other complications.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, João Pereira Figueira, Sobha Sivaprasad, John G Lawrenson, Tunde Peto, David Steel   +14 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Ten steps to innovative dissemination

, 2018
Research dissemination in the 21st Century isn't just articles, books and conference presentations. Open Science shows the way ahead towards dissemination that is participatory, innovative and reaches beyond the boundaries of academia. OpenUP is studying
Vignoli M, Walker M, Luzi D, Stanciauskas V, Pisacane L, Hasani Mavriqi I, Ruggieri R, Banelyte V, Kraker P, Bachleitner R, Gorogh E, Lucic H, Lex E, Sifacaki E, RossHellauer T   +14 more
core  

The clinical effectiveness of trastuzumab for breast cancer: a systematic review

Health Technology Assessment, 2002
R. Lewis, A.-.M Bagnall, C. Forbes, E. Shirran, S. Duffy, J. Kleijnen, R. Riemsma, G. ter Riet   +7 more
doaj   +1 more source

A Novel Granule-Based Formulation as a Health Supplement With an Extended Shelf Life, Derived From the Pulp of Bael (Aegle marmelos) and Various Herbs

Journal of Food Quality
Bael (Aegle marmelos L. Correa) is a fruit known for its historical significance and contains nutritional and medicinal properties. It is a good source of essential vitamins and minerals to maintain human health.
Vipin Kumar, Priyanka Singh, Sanjay Pathak, Sanjay Kumar, Ramesh Kumar Srivastava   +4 more
doaj   +1 more source

Disseminated Sclerosis [PDF]

BMJ, 1947
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Disseminated cysticercosis [PDF]

Neurology, 2015
Rajesh, Jawale, Dhananjay, Duberkar
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source