The Zika Virus Individual Participant Data Consortium: A Global Initiative to Estimate the Effects of Exposure to Zika Virus during Pregnancy on Adverse Fetal, Infant, and Child Health Outcomes [PDF]
This commentary describes the creation of the Zika Virus Individual Participant Data Consortium, a global collaboration to address outstanding questions in Zika virus (ZIKV) epidemiology through conducting an individual participant data meta-analysis ...
Zika Virus Individual Participant Data Consortium
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Responsibilities for receiving and using individual participant data
Background Sharing of individual participant data enhances the value of existing data to generate new evidence and inform decision‐making. While there is strong in‐principle support for data sharing, in practice study data are often difficult to find ...
Kylie E. Hunter +12 more
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Sharing individual participant data: through a systematic reviewer lens [PDF]
An increasing prevalence of data-sharing models, aimed at making individual participant data (IPD) from clinical trials widely available, should facilitate the conduct of systematic reviews and meta-analyses based on IPD. We have assessed these different
Larysa H. M. Rydzewska +2 more
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Identifying relapse predictors in individual participant data with decision trees
Background Depression is a highly common and recurrent condition. Predicting who is at most risk of relapse or recurrence can inform clinical practice. Applying machine-learning methods to Individual Participant Data (IPD) can be promising to improve the
Lucas Böttcher +5 more
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Predicting early intervention outcomes in autism via individual participant data mega-analysis [PDF]
Background Autism early intervention meta-analyses have yielded important insights into questions such as ‘what works’ and ‘for what’ outcomes. However, because these studies primarily rely on study-level summary statistics, they may be limited with ...
Veronica Mandelli +17 more
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Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov.
In June 2017, the International Committee of Medical Journal Editors (ICMJE) announced a requirement that authors reporting the results of clinical trials to journals that follow ICMJE recommendations must include an individual participant data (IPD ...
Emily E Statham +3 more
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Anticoagulation therapy for Lemierre syndrome: a comprehensive review and individual participant data analysis [PDF]
Background Lemierre’s syndrome is a life-threatening infection characterized by septic thrombophlebitis of the internal jugular vein and septic embolism.
Haruka Tsuda +6 more
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Objectives People released from incarceration are at increased risk of death from diverse causes. We aimed to calculate the incidence of all-cause and cause-specific death after release from incarceration and identify individual-level risk factors for ...
Rohan Borschmann +3 more
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BackgroundIn non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control ...
Lamprini Syrogiannouli +36 more
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Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis
Introduction: The airway microbiota has been linked to specific paediatric respiratory diseases, but studies are often small. It remains unclear whether particular bacteria are associated with a given disease, or if a more general, non-specific ...
David T. J. Broderick +49 more
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