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Evidence synthesis software [PDF]

BMJ Evidence-Based Medicine, 2018
It can be challenging to decide which evidence synthesis software to choose when doing a systematic review. This article discusses some of the important questions to consider in relation to the chosen method and synthesis approach. Software can support researchers in a range of ways. Here, a range of review conditions and software solutions.
Sophie Elizabeth Park, James Thomas
openaire   +4 more sources

Network meta-analysis of eribulin versus other chemotherapies used as second- or later-line treatment in locally advanced or metastatic breast cancer

BMC Cancer, 2021
Background Eribulin mesylate (ERI; Halaven®) is a microtubule inhibitor approved in the United States for metastatic breast cancer patients with at least two prior chemotherapy regimens for metastatic breast cancer, and in the European Union in locally ...
Qi Zhao, Rachel Hughes, Binod Neupane, Kristin Mickle, Yun Su, Isabelle Chabot, Marissa Betts, Ananth Kadambi   +7 more
doaj   +1 more source

Structured expert elicitation to inform long-term survival extrapolations using alternative parametric distributions: a case study of CAR T therapy for relapsed/ refractory multiple myeloma

BMC Medical Research Methodology, 2022
Background Our aim was to extend traditional parametric models used to extrapolate survival in cost-effectiveness analyses (CEAs) by integrating individual-level patient data (IPD) from a clinical trial with estimates from experts regarding long-term ...
Dieter Ayers, Shannon Cope, Kevin Towle, Ali Mojebi, Thomas Marshall, Devender Dhanda   +5 more
doaj   +1 more source

A Path to Improved Alzheimer’s Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer’s Disease from the CLARITY AD Trial

Neurology and Therapy, 2023
Introduction Alzheimer’s disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA.
Amir Abbas Tahami Monfared, Weicheng Ye, Aditya Sardesai, Henri Folse, Ameya Chavan, Elena Aruffo, Quanwu Zhang   +6 more
doaj   +1 more source

Estimated Societal Value of Lecanemab in Patients with Early Alzheimer’s Disease Using Simulation Modeling

Neurology and Therapy, 2023
Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with memory, cognitive, and behavioral deficits, and brings significant economic burden on caregivers and healthcare systems.
Amir Abbas Tahami Monfared, Weicheng Ye, Aditya Sardesai, Henri Folse, Ameya Chavan, Kang Kang, Quanwu Zhang   +6 more
doaj   +1 more source

The Pandora’s Box of Evidence Synthesis and the case for a living Evidence Synthesis Taxonomy

BMJ Evidence-Based Medicine, 2022
Have we, as an evidence-based health community, opened the Pandora's box of evidence synthesis? There now exists a plethora of overlapping evidence synthesis approaches and duplicate, redundant and poor-quality reviews.1-4 After years of advocating for the need for systematic reviews of the evidence, there is a risk that this message been disseminated ...
Munn, Z., Pollock, D., Barker, T.H., Stone, J., Stern, C., Aromataris, E., Schünemann, H.J., Clyne, B., Khalil, H., Mustafa, R.A., Godfrey, C., Booth, A., Tricco, A.C., Pearson, A.   +13 more
openaire   +4 more sources

Recent changes to adult national immunization programs for pneumococcal vaccination in Europe and how they impact coverage: A systematic review of published and grey literature

Human Vaccines & Immunotherapeutics, 2023
Despite widespread use of pneumococcal vaccines throughout Europe, the burden of pneumococcal disease (PD) in adults is considerable. To mitigate this burden, National Immunization Technical Advisory Groups (NITAGs) and Health Technology Assessment (HTA)
Stuti Arya, Nicholas Norton, Puneet Kaushik, Agnes Brandtmüller, Eleana Tsoumani   +4 more
doaj   +1 more source

Vulnerability of populations to malaria after indoor residual spraying is withdrawn from areas where its use has previously been sustained: a protocol for a systematic review

BMJ Open, 2022
Introduction With its proven effectiveness, indoor residual spraying (IRS) as a malaria vector control strategy forms one of the reliable vector control strategies, especially when at least 80% of the population is covered.
Edward Kayongo, Rhona Mijumbi-Deve, Philip Orishaba, Pastan Lusiba, Caroline Nakalema, Peter Kasadha, Perez Kirya, Ismael Kawooya   +7 more
doaj   +1 more source

Public health impact of UK COVID-19 booster vaccination programs during Omicron predominance

Expert Review of Vaccines, 2023
Background We aimed to estimate the public health impact of booster vaccination against COVID-19 in the UK during an Omicron-predominant period. Research design and methods A dynamic transmission model was developed to compare public health outcomes for ...
Diana Mendes, Ruth Chapman, Elena Aruffo, Peter Gal, Jennifer L. Nguyen, Libby Hamson, Manuela Di Fusco, Carole Czudek, Jingyan Yang   +8 more
doaj   +1 more source

Bias Modelling in Evidence Synthesis [PDF]

Journal of the Royal Statistical Society Series A: Statistics in Society, 2008
SummaryPolicy decisions often require synthesis of evidence from multiple sources, and the source studies typically vary in rigour and in relevance to the target question. We present simple methods of allowing for differences in rigour (or lack of internal bias) and relevance (or lack of external bias) in evidence synthesis.
Turner, RM, Spiegelhalter, DJ, Smith, GCS, Thompson, SG   +3 more
openaire   +3 more sources