Results 11 to 20 of about 1,370,629 (264)

Early Childhood Development Programs in Low Middle-Income Countries for Rearing Healthy Children: A Systematic Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Early Childhood Development (ECD) includes physical, social, emotional, cognitive and motor development in first eight years of life. Positive parenting, strong families, and encouraging, stimulating environments are critical to a child’s ...
Mahalaqua Nazli Khatib   +4 more
doaj   +1 more source

A new ecosystem for evidence synthesis [PDF]

open access: yesNature Ecology & Evolution, 2020
Synthesizing evidence is an essential part of scientific progress, but it is often done in a slow and uncoordinated manner, sometimes producing misleading conclusions. Here, we propose the idea of an 'open synthesis community' to resolve this pressing issue.
Nakagawa, Shinichi   +41 more
openaire   +5 more sources

Utility value estimates in cardiovascular disease and the effect of changing elicitation methods: a systematic literature review

open access: yesHealth and Quality of Life Outcomes, 2020
Objective Identify the most recent utility value estimates for cardiovascular disease (CVD) via systematic literature review (SLR) and explore trends in utility elicitation methods in the last 6 years.
Marissa Blieden Betts   +7 more
doaj   +1 more source

Correlation Between Early Time-to-Event Outcomes and Overall Survival in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving Definitive Chemoradiation Therapy: Systematic Review and Meta-Analysis

open access: yesFrontiers in Oncology, 2022
BackgroundOverall survival (OS) is the most patient-relevant outcome in oncology; however, in early cancers, large sample sizes and extended follow-up durations are needed to detect statistically significant differences in OS between interventions.
Christopher M. Black   +7 more
doaj   +1 more source

Effectiveness of pharmacist home visits for individuals at risk of medication-related problems: a systematic review and meta-analysis of randomised controlled trials

open access: yesBMC Health Services Research, 2020
Background Medication mismanagement is a major cause of both hospital admission and nursing home placement of frail older adults. Medication reviews by community pharmacists aim to maximise therapeutic benefit but also minimise harm.
Rebecca A. Abbott   +5 more
doaj   +1 more source

Evidence synthesis in prognosis research [PDF]

open access: yesDiagnostic and Prognostic Research, 2019
Over the past few years, evidence synthesis has become essential to investigate and improve the generalizability of medical research findings. This strategy often involves a meta-analysis to formally summarize quantities of interest, such as relative treatment effect estimates.
Thomas P.A. Debray   +3 more
openaire   +3 more sources

A fresh approach to evidence synthesis [PDF]

open access: yesNature, 2018
For most conservation interventions, insufficient evidence exists for investigators to be able to conduct a meta-analysis for each species or genus. However, by being apprised of studies that examine how a particular intervention has worked for an order — for birds in general, say — practitioners can better weigh up the chances of success for their ...
Sutherland, William J   +1 more
openaire   +2 more sources

Risk prediction models for diabetic foot ulcer development or amputation: a review of reviews

open access: yesJournal of Foot and Ankle Research, 2023
Background In adults with diabetes, diabetic foot ulcer (DFU) and amputation are common and associated with significant morbidity and mortality. Purpose Identify tools predicting risk of DFU or amputation that are prognostically accurate and clinically ...
Anjum S. Kaka   +8 more
doaj   +1 more source

Sharing space at the research table: exploring public and patient involvement in a methodology priority setting partnership

open access: yesResearch Involvement and Engagement, 2023
Background Public and patient involvement aims to improve research quality, relevance, and appropriateness. Despite an increasing evidence base on the influence of public involvement in health research, the role of involvement in methodology research (i ...
Nikita N. Burke   +8 more
doaj   +1 more source

Rethinking credible evidence synthesis [PDF]

open access: yesBMJ, 2012
Government regulators and systematic reviewers both aim to generate an accurate understanding of the effects of interventions. However, the methods they use, and the evidence they consider, are different. Although both focus on randomised clinical trials for determining safety and efficacy, the mostly academic community of systematic reviewers ...
Doshi, Peter   +2 more
openaire   +5 more sources

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