Results 11 to 20 of about 1,370,629 (264)
Early Childhood Development Programs in Low Middle-Income Countries for Rearing Healthy Children: A Systematic Review [PDF]
Introduction: Early Childhood Development (ECD) includes physical, social, emotional, cognitive and motor development in first eight years of life. Positive parenting, strong families, and encouraging, stimulating environments are critical to a child’s ...
Mahalaqua Nazli Khatib +4 more
doaj +1 more source
A new ecosystem for evidence synthesis [PDF]
Synthesizing evidence is an essential part of scientific progress, but it is often done in a slow and uncoordinated manner, sometimes producing misleading conclusions. Here, we propose the idea of an 'open synthesis community' to resolve this pressing issue.
Nakagawa, Shinichi +41 more
openaire +5 more sources
Objective Identify the most recent utility value estimates for cardiovascular disease (CVD) via systematic literature review (SLR) and explore trends in utility elicitation methods in the last 6 years.
Marissa Blieden Betts +7 more
doaj +1 more source
BackgroundOverall survival (OS) is the most patient-relevant outcome in oncology; however, in early cancers, large sample sizes and extended follow-up durations are needed to detect statistically significant differences in OS between interventions.
Christopher M. Black +7 more
doaj +1 more source
Background Medication mismanagement is a major cause of both hospital admission and nursing home placement of frail older adults. Medication reviews by community pharmacists aim to maximise therapeutic benefit but also minimise harm.
Rebecca A. Abbott +5 more
doaj +1 more source
Evidence synthesis in prognosis research [PDF]
Over the past few years, evidence synthesis has become essential to investigate and improve the generalizability of medical research findings. This strategy often involves a meta-analysis to formally summarize quantities of interest, such as relative treatment effect estimates.
Thomas P.A. Debray +3 more
openaire +3 more sources
A fresh approach to evidence synthesis [PDF]
For most conservation interventions, insufficient evidence exists for investigators to be able to conduct a meta-analysis for each species or genus. However, by being apprised of studies that examine how a particular intervention has worked for an order — for birds in general, say — practitioners can better weigh up the chances of success for their ...
Sutherland, William J +1 more
openaire +2 more sources
Risk prediction models for diabetic foot ulcer development or amputation: a review of reviews
Background In adults with diabetes, diabetic foot ulcer (DFU) and amputation are common and associated with significant morbidity and mortality. Purpose Identify tools predicting risk of DFU or amputation that are prognostically accurate and clinically ...
Anjum S. Kaka +8 more
doaj +1 more source
Background Public and patient involvement aims to improve research quality, relevance, and appropriateness. Despite an increasing evidence base on the influence of public involvement in health research, the role of involvement in methodology research (i ...
Nikita N. Burke +8 more
doaj +1 more source
Rethinking credible evidence synthesis [PDF]
Government regulators and systematic reviewers both aim to generate an accurate understanding of the effects of interventions. However, the methods they use, and the evidence they consider, are different. Although both focus on randomised clinical trials for determining safety and efficacy, the mostly academic community of systematic reviewers ...
Doshi, Peter +2 more
openaire +5 more sources

