Results 101 to 110 of about 95,025 (271)

An iterative approach to evaluating impact of CTSA projects using the translational science benefits model

Frontiers in Health Services
IntroductionDemonstrating the relevance and impact of translational research across diverse settings is crucial making the research-to-practice pipeline more efficient.
Kera Swanson, Nicole A. Stadnick, Nicole A. Stadnick, Nicole A. Stadnick, Isaac Bouchard, Isaac Bouchard, Zeying Du, Lauren Brookman-Frazee, Lauren Brookman-Frazee, Lauren Brookman-Frazee, Gregory A. Aarons, Gregory A. Aarons, Gregory A. Aarons, Emily Treichler, Emily Treichler, Emily Treichler, Maryam Gholami, Borsika A. Rabin, Borsika A. Rabin   +18 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Enhancing Dissemination, Implementation, and Improvement Science in CTSAs through Regional Partnerships [PDF]

, 2015
Background and Importance: Challenges in healthcare policy and practice have stimulated interest in dissemination and implementation science. The Institute of Medicine Committee on the Clinical Translational Science Award (CTSA) program recommended ...
Mittman, BS, Ibrahima C. Sankaré, Kuo, T, Brown, Arleen F, Katrina Kubicek, Stefanie D. Vassar, Tony Kuo, Arturo B. Martinez, Brian S. Mittman, Inkelas, Moira, Gould, M, Martinez, Arturo B, Brown, AF, Martinez, AB, Kubicek, Katrina, Mittman, Brian S, Moira Inkelas, Kubicek, K, Mahajan, A, Michael Gould, Gould, Michael, Mahajan, Anish, Vassar, SD, Kuo, Tony, Sankaré, IC, Sankaré, Ibrahima C, Inkelas, M, Arleen F. Brown, Vassar, Stefanie D, Anish Mahajan   +29 more
core   +1 more source

Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics): results of a 28-site cluster-randomized type 3 hybrid trial

Implementation Science
Background Contingency management (CM), a behavioral treatment that incentivizes patients for attaining treatment goals, is a highly effective adjunct to medication for opioid use disorder.
Sara J. Becker, Tim Janssen, Tim Souza, Bryan Hartzler, Carla J. Rash, Kira DiClemente-Bosco, Bryan R. Garner   +6 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Saf Sci [PDF]

Objective:A limited focus on dissemination and implementation (D&I) science has hindered the uptake of evidence-based interventions (EBIs) that reduce workplace morbidity and mortality.

core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

The implementation in context (icon) framework: a meta-framework of context for dissemination and implementation science

, 2023
The implementation in context (icon) framework: a meta-framework of context for dissemination and implementation ...
Melissa Demery Varin (16817523), Shelly A Li (20935052), Ian D Graham (13366437), Wilmer J Santos (16817514), Alison Hutchinson (13057050), Janet E Squires (13448796)   +5 more
core  

Implementing TeamMAPPS: Formative qualitative findings from the dissemination and implementation study of a new evidence-based team science intervention

Journal of Clinical and Translational Science
Introduction: Team Methods to Advance Processes and Performance in Science (TeamMAPPS) is an evidence-based Team Science competency model and intervention. TeamMAPPS was developed by experts in the Science of Team Science with translational teams in mind.
Stephen Molldrem, Heidi Luft, Jeffrey S. Farroni, Elizabeth J. Lyons, Kevin Wooten   +4 more
doaj   +1 more source