Results 91 to 100 of about 95,025 (271)

Dissemination and Implementation Science: Research for the Real World Medical Family Therapist

, 2014
Dissemination and Implementation (D&I) Science is an evolving field of models and methods aimed at closing the research-practice gap. This chapter provides an overview of D&I Science with particular emphasis on its relevance for academic and clinical ...
Polaha, Jodi, Beth Nolan, Jodi Polaha, Nolan, Beth   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dissemination and Implementation of Evidence-Based Psychological Interventions

, 2015
Chapter 13 explores the current status of research and future directions for the dissemination and implementation of evidence-based psychological interventions, including further emphasis on dissemination and implementation science, standardization of ...
R. Kathryn McHugh, David H. Barlow
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Clarifying dissemination outcomes: a taxonomy to advance dissemination science

Implementation Science
Background Dissemination science lacks shared language for specifying what dissemination strategies are designed to achieve. Without clearly defined outcomes, researchers cannot design studies that explain why dissemination strategies succeed or fail ...
Kristi E. Gamarel, Katherine G. Merrill, Sybil Hosek, Lisa B. Hightow-Weidman   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Dissemination Research Logic Model for advancing dissemination science and practice

Background Relative to implementation science, dissemination science is at an earlier stage of development and lacks a tool for specifying and visually depicting the components of the dissemination process.
Sybil Hosek, Katherine G. Merrill, Kristi E. Gamarel, Sylvie Naar, Lisa B. Hightow-Weidman   +4 more
core   +1 more source

Disseminating research findings: what should researchers do? A systematic scoping review of conceptual frameworks [PDF]

, 2010
Background: Addressing deficiencies in the dissemination and transfer of research-based knowledge into routine clinical practice is high on the policy agenda both in the UK and internationally.
Petticrew, Mark, Paul M Wilson, Irwin Nazareth, Nazareth, Irwin, Calnan, Mike W., Calnan, MW, Mike W Calnan, Mark Petticrew, Calnan, Mike W, Wilson, Paul M.; id_orcid, Wilson, PM, Wilson, Paul M, Nazareth, I, Petticrew, M, Petticrew Mark, Nazareth Irwin, Calnan Mike W, Wilson Paul M   +17 more
core   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source