Results 71 to 80 of about 95,025 (271)

The effects of neighborhood perceptions on response to a technology-assisted parenting intervention for adolescent substance use: protocol of a diversity supplement to parent SMART (Substance Misuse in Adolescents in Residential Treatment)

Addiction Science & Clinical Practice
Background It is well established that an adolescent’s neighborhood is associated with their likelihood of developing a substance use disorder. The availability of drugs, lack of access to resources, and exposure to violence are all associated with ...
Zabin Patel-Syed, Sarah A. Helseth, Robert Rosales, Tim Janssen, Kelli Scott, Sara J. Becker   +5 more
doaj   +1 more source

Identifying strategies to promote team science in dissemination and implementation research [PDF]

Journal of Clinical and Translational Science, 2019
AbstractIntroduction:Scientific endeavors are increasingly carried out by teams of scientists. While there is growing literature on factors associated with effective science teams, little is known about processes that facilitate the success of dissemination and implementation (D&I) teams studying the uptake of healthcare innovations.
Gregory A. Aarons, Kendal Reeder, Christopher J. Miller, Nicole A. Stadnick   +3 more
openaire   +5 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Terminology for Dissemination and Implementation Research

, 2017
In order for a field to prosper and thrive, a common language is essential. As is often the case when many disciplines and numerous organizations converge in development of a field, dissemination and implementation research is still characterized by ...
Ross C. Brownson, Borsika A. Rabin
core   +1 more source

Identifying unique barriers to implementing rural emergency department-based peer services for opioid use disorder through qualitative comparison with urban sites

Addiction Science & Clinical Practice, 2022
Background In an effort to address the current opioid epidemic, a number of hospitals across the United States have implemented emergency department-based interventions for engaging patients presenting with opioid use disorder. The current study seeks to
Dennis P. Watson, Monte D. Staton, Nicole Gastala   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

From glitter to gold: recommendations for effective dashboards from design through sustainment

Implementation Science
Background Dashboards—tools that compile and summarize key performance data—have become increasingly utilized for supporting data organization and decision-making processes across various fields, such as business, economics, healthcare, and policy.
Fernanda S. Rossi, Meredith C. B. Adams, Gregory Aarons, Mark P. McGovern   +3 more
doaj   +1 more source

Implementation outcomes of the IMARA-South Africa mother-daughter HIV/STI prevention intervention: A mixed-methods study

Journal of Clinical and Translational Science
Background: IMARA-South Africa (SA) is an HIV/STI prevention program for adolescent girls and young women (AGYW) and their female caregivers (FC). We examined six implementation outcomes of IMARA-SA (acceptability, appropriateness, feasibility, reach ...
Katherine G. Merrill, Millicent Atujuna, Saba Ahmed, Erin Emerson, Anelisiwe Ngcuka, Erin Jaworski, Linda-Gail Bekker, Natasha Crooks, Alyssa Debra, Geri Donenberg   +9 more
doaj   +1 more source

Implementation research in Primary Care (Part 2): How to conduct implementation research? [PDF]

Malaysian Family Physician
This paper is the second paper on implementation research in primary care. This paper outlines key processes for conducting implementation research, emphasising the importance of selecting relevant theories, models, and frameworks to guide each stage ...
Wen Ting Tong, Chor Yau Ooi, Anne Sales, Chirk Jenn Ng   +3 more
doaj   +1 more source