Results 111 to 120 of about 2,385 (288)

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

open access: yesAdvanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li   +6 more
wiley   +1 more source

Harmoniser les dissensions [PDF]

open access: yes, 2010
Cet article examine certaines tendances récentes, apparemment contraires, du système de censure chinois dans le domaine de la littérature et du cinéma. Alors qu’en janvier 2007, les mesures prises envers les « huit livres interdits » semblaient démontrer
Veg, Sebastian
core  

Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics

open access: yesAdvanced Science, EarlyView.
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai   +3 more
wiley   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

open access: yesAdvanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun   +15 more
wiley   +1 more source

4429. Dépêche de Tommaso Tebaldo au duc de Milan ; nouvelles politiques de France ; dissensions entre le roi et le dauphin ; occupation du Dauphiné par Charles VII (7 décembre 1456), publiée par E. Charavay, Lettres de Louis XI dauphin, I, 266-277

open access: yes, 1904
4429. Dépêche de Tommaso Tebaldo au duc de Milan ; nouvelles politiques de France ; dissensions entre le roi et le dauphin ; occupation du Dauphiné par Charles VII (7 décembre 1456), publiée par E. Charavay, Lettres de Louis XI dauphin, I, 266-277.
Molinier, Auguste
core  

Dissensions Within the Early Church

open access: yes, 1967
No abstract ...
Cullmann, Oscar
core   +1 more source

Automating Chemical Reasoning in High‐Throughput Phase Identification With a Probabilistic, LLM‐Guided Framework

open access: yesAdvanced Science, EarlyView.
Autonomous laboratories can now synthesize materials faster than experts can interpret the resulting diffraction data. A probabilistic framework combines refinement‐fit metrics with large language model‐derived chemical reasoning to rank competing phase interpretations and flag those unsuitable for autonomous use.
Olympia Dartsi   +7 more
wiley   +1 more source

Decision Support Frameworks in Public Health Emergencies: A Systematic Review of Dynamic Models in Complex Contexts. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Príncipe AS   +5 more
europepmc   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

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