Results 61 to 70 of about 5,270 (307)

Глазами „другого” (заметки о прозе Е.Г. Эткинда)

open access: yesPoznańskie Studia Slawistyczne, 2014
In the article E.G. Etkind’s prose is discussed from the point of view of its place and role in the dissident movement in the Soviet Russia. The particular attention is paid of Etkind’s ideological differences with the political regime and of the Jewish
Владислав Кривонос
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Muzeum niepokorności

open access: yesPoznańskie Studia Slawistyczne, 2014
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Žarko Paić
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

L'évolution des mouvements religieux dissidents en Afrique (1862-1967)

open access: yes, 1968
Barrett David B. L'évolution des mouvements religieux dissidents en Afrique (1862-1967). In: Archives de sociologie des religions, n°25, 1968. pp.
Barrett, David B., David B. Barrett
core   +1 more source

EVOLUTION OF THE «RETURN TO EUROPE» CONCEPT IN THE VISEGRAD COUNTRIES [PDF]

open access: yesНаучно-аналитический вестник Института Европы РАН
This article analyzes the discursive project of «return to Europe» in the Visegrad Group countries during the period 1990s – 2000s. The author reconstructs the intellectual origins of the concept, traces its transformation into an instrument of state ...
Dotsenko Pavel
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Chinese Intellectual Dissidents

open access: yes, 1991
The concept of dissident under consideration in this study reveals that political and loyal dissent, non-conformity and well-meaning criticisms of government\u27s wrong doings, and even the quest for democracy exist in China as they do in the West ...
Liu, Meiru
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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