Results 41 to 50 of about 7,536 (299)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Discourse Beyond Borders: Periodicals, Dissidents, and European Cultural Spaces
Journal of European Periodical Studies, 2018 Émigré periodicals in Cold War Europe have long been considered isolated islands of Central and East European communities with limited relevance. In the second half of the Cold War, some of these periodicals functioned as crucial intersections of ...
doaj +2 more sources
Sprawy Narodowościowe. Seria nowa, 2016 Central Europe – a community of texts. Intertextuality as a plane of functioning and maintaining the myth of Central Europe In this article I examine two primary (sets of) questions: 1.
Ilija Upalevski
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Cyber Dissidents: Harbingers of Change
, 2014 This piece of research is concerned with gauging the public’s cumulative shift in opinion in the wake of the two most notable instances of cyber whistle blowing.
Ruzicka, Cory
core +1 more source
The Writing on the Wall: National and Global Implications of the Ruling Chinese Communist Party’s Domestic and Foreign Policies [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2016 The December 2015 crackdown on labour activists was the culmination of a year of the Chinese Communist Party regime’s war on China’s civil society kicked off with the arrests of the “Feminist Five” in March, followed by the infamous crackdown on civil ...
Emile Kok-Kheng Yeoh
doaj
Allen Ginsberg in Search of Soviet Dissidents [PDF]
Литература двух АмерикThe article reconstructs the history of the 1965 visit to the Soviet Union by Allen Ginsberg, a key figure of the American Beat Generation. Using archival materials from the Foreign Commission of the USSR Union of Writers introduced into scholarly ...
Aleksandra S. Surkova
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Глазами „другого” (заметки о прозе Е.Г. Эткинда)
Poznańskie Studia Slawistyczne, 2014 In the article E.G. Etkind’s prose is discussed from the point of view of its place and role in the dissident movement in the Soviet Russia. The particular attention is paid of Etkind’s ideological differences with the political regime and of the Jewish
Владислав Кривонос
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source