Results 141 to 150 of about 219,079 (300)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Energy and damage analysis of fractured sandstone under true triaxial cyclic loading

open access: yesMeikuang Anquan
Exploring the energy evolution of fractured sandstone under true triaxial cyclic loading is helpful to clarify the law of rock damage and failure. The evolution characteristics of total absorbed energy, elastic energy, dissipated energy and plastic ...
Xiyuan LI   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Wave Energy Dissipation in Rockfill

open access: yesCoastal Engineering 1972, 1972
Very little literature exists on the subject of unsteady non-Darcy flow in coarse granular media. However, unsteady non-Darcy flow is encountered in a few important hydraulic problems, for example, (a) Wave absorption and transmission in rubble-mound break-waters; (b) Water level fluctuations in the rockfill and filter zones of a dam subjected to wave ...
openaire   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Boosting of Dissipated Renewable Energy Systems Towards Sustainability in Kazakhstan

open access: yesEnvironmental and Climate Technologies
The study aims to develop a methodology for selecting and justifying a multi-energy hub based on renewable energy sources for agricultural complex.
Khabdullina Guldana   +4 more
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

ENERGY DISSIPATED IN ELASTIC-PLASTIC AND ELASTIC-VISCOPLASTIC SOLIDS

open access: yesJournal of the Mechanical Behavior of Materials, 2000
Jansohn, W.   +2 more
doaj   +1 more source

A comparison of pop and chop to divide and conquer in resident cataract surgery

open access: yesClinical Ophthalmology, 2016
Fredric J Gross, Debra E Garcia-Zalisnak, Courtney E Bovee, Joy D Strawn Department of Ophthalmology, Eastern Virginia Medical School, Norfolk, VA, USA Abstract: In this randomized prospective study, the cumulative dissipated energy and case time of ...
Gross FJ   +3 more
doaj  

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