Results 41 to 50 of about 27,998 (260)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Fatigue Limit Estimation Based on Dissipated Energy of Butt Laser-Welded Joints

open access: yesEngineering Proceedings
This study established a rapid estimation method for the fatigue limit of laser welds of aluminum alloys in order to optimize welding conditions, an important factor in ensuring the safety and reliability of laser welding.
Takumi Yamamoto   +5 more
doaj   +1 more source

Investigation of Energy Mechanism and Acoustic Emission Characteristics of Mudstone with Different Moisture Contents

open access: yesShock and Vibration, 2018
Characteristics of energy accumulation, evolution, and dissipation in conventional triaxial compression of mudstones with different moisture contents were explored. Stress-strain relations and acoustic emission (AE) characteristics of the deformation and
Jingdong Jiang, Jie Xu
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Triaxial experimental study on mechanical behavior, acoustic emission characteristics, and energy evolution of coral sand grouting consolidated body under different confining pressures

open access: yesCase Studies in Construction Materials
This study conducted triaxial compression tests on coral sand grouting consolidated body, incorporating Acoustic Emission (AE) testing to analyze the mechanical properties, AE characteristics, and energy evolution under different strain rates.
Zhenwei Liu   +5 more
doaj   +1 more source

Analysis of energy dissipation characteristics in granite under high confining pressure cyclic load

open access: yesAlexandria Engineering Journal, 2020
With cyclic high in-situ stress, the rock will damage and lead to serious engineering geological disasters. A property of rock failure is the rock damage evolution driven by energy.
Dongjie Yang, Jianhua Hu, Xiaotian Ding
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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