Results 41 to 50 of about 709,863 (314)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dissociation is an “escape way” from unbearable traumatic events, a tendency for denying or oppressing traumas and their effects as well as the emotions stemming from them.
Erdinç ÖZTÜRK +2 more
doaj
Dissociative states in dreams and brain chaos: Implications for creative awareness
This article reviews recent findings indicating some common brain processes during dissociative states and dreaming with the aim to outline a perspective that neural chaotic states during dreaming can be closely related to dissociative states that may ...
Petr eBob, Olga eLouchakova
doaj +1 more source
Novel details on the dissociation of casein micelle suspensions as a function of pH and temperature
: Membrane filtration is a widespread process for fractionation and recombination of milk components. Although the dissociation of micellar caseins has been studied in detail in skim milk, it is important to better understand the dissociation dynamics ...
Thea Lykkegaard M⊘ller +2 more
doaj +1 more source
Introduction Today's assessment instruments for dissociation among adolescents are either relatively extensive or are specifically designed to identify either psychoform or somatoform dissociation.
Green, Sara +7 more
core +1 more source
Mechanism of Dissociation Kinetics in Polyelectrolyte Complex Micelles [PDF]
Polyelectrolyte-based nanoscale self-assemblies, such as micelles, possess diverse desirable attributes such as capability for sequestering and protecting biomacromolecules against inhospitable environments, responsiveness to external stimuli,
Matthew, Tirrell, Jeffrey, Ting, Hao, Wu
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The current psychopharmacological treatment approaches for major depression focus on monoaminergic interventions, which are ineffective in a large proportion of patients.
Adam Włodarczyk +1 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

