Results 121 to 130 of about 390,267 (298)

Chemical Degradation of OLED Host Materials: The Role of Non-Local Interaction in Electronic Excited States [PDF]

, 2019
Department of PhysicsOrganic light-emitting devices (OLEDs) have been attracted to both academia and industry, because of their wide applications and remarkable advances in display.
Lee, Seunghyun
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Crossover from the Ultracold to the Quasiclassical Regime in State-Selected Photodissociation

, 2018
Processes that break molecular bonds are typically observed with molecules occupying a mixture of quantum states and successfully described with quasiclassical models, while a few studies have explored the distinctly quantum mechanical low-energy regime.
Kondov, S. S., Lee, C. -H., Majewska, I., McDonald, M., McGuyer, B. H., Moszynski, R., Zelevinsky, T.   +6 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Mechanistic study of moisture corrosion of FeCr alloys in molten salts by ab-initio molecular dynamics simulations

Communications Materials
Molten salts are promising for various energy applications including fuel and solar cells and nuclear energy. These applications face a common challenge: corrosion of structural materials by impurities such as H2O.
Anton Schneider, David Andersson, Yongfeng Zhang   +2 more
doaj   +1 more source

Photoprocesses in protoplanetary disks

, 2006
Circumstellar disks are exposed to intense ultraviolet radiation from the young star. In the inner disks, the UV radiation can be enhanced by more than seven orders of magnitude compared with the average interstellar field, resulting in a physical and ...
Aikawa, Augereau, Bastiaan Jonkheid, Bergin, Brittain, Buenker, Calvet, Chiang, Clampin, Connors, D?Alessio, Dent, Draine, Dunning, Dutrey, Ewine F. van Dishoeck, Feigelson, Geers et al., Gorti, Greaves, Gredel, Guest, Habing, Hauschildt, Herbig, Hollenbach, Honjou, Huebner, Jonkheid, Jonkheid, Kamp, Kamp, Kamp, Kessler-Silacci, Kirby, Kirby, Koch, Koch, Lavendy, Lee, Lee, Lee, Lee, Lee, Lepp, Li, Lyons, Marc C. van Hemert, Markwick, Min, Muzerolle, Nee, Nee, Ogawa, Okabe, Pouilly, R?melt, Roberge, Roberge, Shen, Shih, Spaans, St?uber, St?uber, Suto, Suto, Suto, Suto, Sylvester, Theodorakopoulos, Thi, van Boekel, van Dishoeck, van Dishoeck, van Dishoeck, van Dishoeck, van Dishoeck, van Zadelhoff, Watanabe, Weidenschilling, Willacy, Yoshino   +81 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source