Results 101 to 110 of about 463,636 (339)

Stability Analysis of Methane Hydrate-Bearing Soils Considering Dissociation

open access: yesEnergies, 2015
It is well known that the methane hydrate dissociation process may lead to unstable behavior such as large ground deformations, uncontrollable gas production, etc. A linear instability analysis was performed in order to investigate which variables have a
Hiromasa Iwai   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Statistical evaporation of rotating clusters. IV. Alignment effects in the dissociation of nonspherical clusters

open access: yes, 2004
Unimolecular evaporation in rotating, non-spherical atomic clusters is investigated using Phase Space Theory in its orbiting transition state version. The distributions of the total kinetic energy release epsilon_tr and the rotational angular momentum ...
Amar   +36 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Analysis of temperature and pressure distribution of containers for nuclear waste material disposal in space [PDF]

open access: yes
A computer program was adapted from a previous generation program to analyze the temperature and internal pressure response of a radioactive nuclear waste material disposal container following impact on the earth. This program considers component melting,
Parker, W. G., Vanbibber, L. E.
core   +1 more source

Dissociation and pain perception : an experimental investigation [PDF]

open access: yes, 2006
textDissociative symptoms and abnormalities in pain perception have been associated with a range of disorders. We tested whether experimentally induced increases in state dissociation would cause an analgesic response, and whether this effect would be ...
Horowitz, Jonathan David
core  

Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance

open access: yesJournal of Immunology Research, 2016
The aim of this study was, at the assay development stage and thus with an appropriate degree of rigor, to select the most appropriate technology platform and sample pretreatment procedure for a clinical ADA assay.
Justine Collet-Brose   +5 more
doaj   +1 more source

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