Results 81 to 90 of about 177,329 (291)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Influence of degree of ammonia dissociation on nitriding of stainless steels

, 2009
Досліджено вплив ступеня дисоціації аміаку на будову, склад та поверхневу твердість сталей 12Х13, 40Х13, 12Х17 після газового азотування. Оптимальний ступінь дисоціації аміаку при температурі азотування 550 оС становить 25 – 35 %, забезпечує високу ...
Більченко, О.В., Хижняк, В.Г., Курило, Н.А.   +2 more
core   +1 more source

Large Rapidity Gap Method to Select Soft Diffraction Dissociation at the LHC

Advances in High Energy Physics, 2016
In proton-proton (pp) collisions, any process involves exchanging the vacuum quantum numbers is known as diffractive process. A diffractive process with no large Q2 is called soft diffractive process.
Emily Nurse, Sercan Sen
doaj   +1 more source

Quasinormal modes for quarkonium in a plasma with magnetic fields

Physics Letters B, 2019
Heavy vector mesons detected after a heavy ion collision are important sources of information about the quark gluon plasma. The fraction of such particles that survive the plasma phase and reach the detectors is related to the dissociation degree inside ...
Nelson R.F. Braga, Luiz F. Ferreira
doaj   +1 more source

Association and dissociation: individual differences [PDF]

, 1990
This study attempts to integrate two independent research literatures which lie within the broad area of pain and cognitive aspects of pain: 1) research in pain and clinical pain treatment, and; 2) research in athletes' pain coping strategies.
McCann, Sean Cairbre
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Process Mineralogy of Solid Waste Minerals from Lijiagou Spodumene Mine and Occurrence State of Lithium

Kuangchan zonghe liyong
This is an article in the field of process mineralogy. Lithium is an important rare metal, which is widely used in metallurgy, machinery, chemical industry, ceramics, glass building materials and other industries, and becomes an important part of new ...
Yanqing CHEN, Junfeng WU, Lin CHEN, Panpan WANG   +3 more
doaj   +1 more source

Childhood stress and dissociation in a college population

, 1989
p. 017-023Two studies are reported demonstrating that individual differences in dissociation in college students are positively related to differences in self-reported stressful or traumatic experiences in youth.
McRoberts, Gerald, Tollefson, Christine, Sanders, Barbara   +2 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source