Results 61 to 70 of about 3,021,829 (254)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Journal of MMIJ, 2017 Depressurization process is regarded as the most effective process for gas recovery method from the viewpoints of gas productivity and economic efficiency among in-situ dissociation processes of Methane Hydrate (MH) existing in marine sediments. However,
Masayo KAKUMOTO +7 more
doaj +1 more source
Dissociative symptoms and the quality of structural integration in borderline personality disorder [PDF]
, 2014 Background Transient dissociation is a core feature of borderline personality disorder (BPD). Dissociation is characterized by detachment from reality, which can be mild (e.g. daydreaming) to severe (e.g. depersonalization, amnesia).
Sole, S
core
, 2017 Acylborons, as a growing class of boron reagents, were successfully applied to amide ligation and showed potential in chemoselective bioconjugation reactions in recent years.
Yujie Liang (1519678) +5 more
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Multi-factor sensitivity analysis on the stability of submarine hydrate-bearing slope
China Geology, 2018 : There are many factors affecting the instability of the submarine hydrate-bearing slope (SHBS), and the interaction with hydrate is very complicated. In this paper, the mechanical mechanism of the static liquefaction and instability of submarine slope ...
Liang Kong +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
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Childhood stress and dissociation in a college population
, 1989 p. 017-023Two studies are reported demonstrating that individual differences in dissociation in college students are positively related to differences in self-reported stressful or traumatic experiences in youth.
McRoberts, Gerald +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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