Results 101 to 110 of about 201,896 (330)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor
Frontiers in Pharmacology, 2017 Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT2A receptor is the mechanism underlying these psychedelic ...
Drew J. Puxty +12 more
doaj +1 more source
Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells
, 2022 Shahnaz Babaei-Abraki +2 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Indian Journal of Psychological Medicine, 2017 Conversion disorders are more prevalent in childhood and adolescence, especially in females. They are usually associated with stressors and symptoms usually reflect a means to avoid the stressor, or also with a primary and secondary gain. This case report involves a similar situation where a young girl was treated successfully with diazepam ...
Arya Jith, Dinesh Narayanan
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A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
, 2011 We present the results of DFT calculations of free energy profiles along the reaction pathways starting from 50% coverage of MoS2 M-edge and 100% coverage of S-edge by sulfur, and leading to 37% coverage, i.e.
Prodhomme, Pierre-Yves +2 more
core +1 more source
Can dissociative amnesia be a residual symptom of prolonged complex post-traumatic stress disorder?
Annals of General PsychiatryBackground Dissociative amnesia, a disorder characterized by impairments in multiple memory areas, is frequently associated with trauma. Complex post-traumatic stress disorder (CPTSD) is marked by mood dysregulation, negative self-concept, and impaired ...
İzzet Çağrı Metin +2 more
doaj +1 more source
Ventriculo-ventricular dissociation∗
The American Journal of Cardiology, 1960 Abstract In open chest experiments in forty-seven dogs, the electrical activity of the two ventricles was studied by means of simultaneously recorded epicardiac leads. In fourteen dogs, four types of ventriculo-ventricular dissociation were observed, namely, fibrillation and flutter; fibrillation and idio-ventricular rhythm; standstill and ...
Malamos, B., Moulopoulos, S.
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Developing an understanding of the relationship between anxiety and dissociation in adolescence [PDF]
, 2023 Katie Lofthouse +2 more
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