Results 141 to 150 of about 50,274 (312)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The role of the precuneus in dissociative seizures: A structural neuroimaging study

open access: yesNeuroImage: Clinical
The neurobiology and neuropsychology of dissociative seizures is increasingly well understood, but a gap remains in understanding the neurobiological underpinnings of one of its core features: dissociation.
Leonie Helmstaedter   +4 more
doaj   +1 more source

Am I nearly there? The effect of anticipated running distance on perceived exertion and attentional focus

open access: yes, 2004
Two studies tested the hypothesis that teleoanticipatory mechanisms regulate the perception of exertion (RPE) in the context of expected exercise duration by the adjustment of attentional focus.
Warwick-Evans, Lawrence   +2 more
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Solar maculopathy and dissociative symptoms: a case report on a patient on buprenorphine opioid replacement therapy

open access: yes, 2022
Solar maculopathy refers to thermal and photochemical macular damage caused by excessive exposure to light.1 Risk factors include behaviour (eg welding, sunbathing), refraction, pupillary size and clarity of ocular media.2 Drugs, both prescribed and ...
Redmayne, James, Lam, Lewis
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Position- and time-sensitive coincident detection of fragments from the dissociative recombination of O-2(+) using a single hexanode delay-line detector

open access: yes, 2005
This contribution describes the use of the RoentDek hexanode delay line detector to detect fragments from the dissociative recombination of O-2(+) in an experiment at the ion storage ring CRYRING, Manne Siegbahn Laboratory, Stockholm. In this experiment,
van der Zande, WJ   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy