Results 51 to 60 of about 201,896 (330)

Dysregulation in cortical reactivity to emotional faces in PTSD patients with high dissociation symptoms

European Journal of Psychotraumatology, 2013
Background: Predominant dissociation in posttraumatic stress disorder (PTSD) is characterized by restricted affective responses to positive stimuli. To date, no studies have examined neural responses to a range of emotional expressions in PTSD with high ...
Aleksandra Klimova, Richard A. Bryant, Leanne M. Williams, Kim Louise Felmingham   +3 more
doaj   +1 more source

Sleep, trauma, fantasy and cognition in dissociative identity disorder, post-traumatic stress disorder and healthy controls: a replication and extension study

European Journal of Psychotraumatology, 2020
Background: Two aetiology models for dissociative identity disorder (DID) have been proposed, namely a childhood Trauma Model and an iatrogenic or Fantasy model.
Lora Dimitrova, Vinuri Fernando, Eline M. Vissia, Ellert R. S. Nijenhuis, Nel Draijer, Antje A. T. S. Reinders   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Dissociation and pain perception : an experimental investigation [PDF]

, 2006
textDissociative symptoms and abnormalities in pain perception have been associated with a range of disorders. We tested whether experimentally induced increases in state dissociation would cause an analgesic response, and whether this effect would be ...
Horowitz, Jonathan David
core  

Dissociation and its biological and clinical associations in functional neurological disorder: systematic review and meta-analysis

BJPsych Open, 2023
Background Studies have reported elevated rates of dissociative symptoms and comorbid dissociative disorders in functional neurological disorder (FND); however, a comprehensive review is lacking.
Malcolm C. Campbell, Abigail Smakowski, Maya Rojas-Aguiluz, Laura H. Goldstein, Etzel Cardeña, Timothy R. Nicholson, Antje A. T. S. Reinders, Susannah Pick   +7 more
doaj   +1 more source

Interference Dissociation [PDF]

Circulation, 1957
Contradirectional interference results when 2 stimuli arising in different foci in any part of the heart spread in opposite directions toward each other. Interference dissociation is defined as that type of dissociation which is due to repetitive contradirectional interference.
R, MILLER, R H, SHARRETT
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Dissociative symptoms mediate the relation between PTSD symptoms and functional impairment in a sample of military members, veterans, and first responders with PTSD

European Journal of Psychotraumatology, 2018
Background: Posttraumatic Stress Disorder (PTSD) is associated with significant functional impairment in important areas, including interpersonal relationships and occupational or educational roles.
Jenna E. Boyd, Alina Protopopescu, Charlene O’Connor, Richard W. J. Neufeld, Rakesh Jetly, Heather K. Hood, Ruth A. Lanius, Margaret C. McKinnon   +7 more
doaj   +1 more source

Maladaptive Daydreaming, Dissociation, and the Dissociative Disorders

Psychiatric Research and Clinical Practice, 2020
Objective Studies on maladaptive daydreaming have shown that it has a number of comorbidities including dissociative disorders, yet no studies have examined the reciprocal relationship.
Colin A. Ross, Jane Ridgway, Nevita George   +2 more
doaj   +1 more source