Results 231 to 240 of about 3,088 (284)

A rapid method for evaluating the behavioral effects of phencyclidine-like dissociative anesthetics in mice

Psychopharmacology, 1991
A simple and rapid method for detecting the behavioral effects of phencyclidine and related dissociative anesthetics is described. Dissociative anesthetics such as phencyclidine (PCP) and dizolcipine, which bind with high affinities at N-methyl-D-aspartate (NMDA) coupled cation channels ("PCP receptors"), produced a dose-related increase in the ...
G E, Evoniuk, R P, Hertzman, P, Skolnick
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Dissociative Anesthetics

2010
Nicola Simola, Micaela Morelli, Tooru Mizuno, Suzanne H. Mitchell, Harriet de Wit, H. Valerie Curran, Celia J. A. Morgan, Stephan G. Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Lawrence H. Price, Grasielle C Kincheski, Leandro J Bertoglio, Antonio Padua Carobrez, Andrea Bari, Roshan Cools, Yogita Chudasama, Stefan Leucht, Yogita Chudasama, William Breitbart, Yesne Alici, Karl Mann, Falk Kiefer, Yesne Alici, William Breitbart, Michael M Morgan, M J Christie, Istvan Bitter, Eileen M. Joyce, Jonathan P Roiser, Darren R Christensen, Warren K. Bickel, Kenneth J. Rhodes, Peter Paul De Deyn, Debby Van Dam, Darrel J. Pemberton, Johannes Mosbacher, Thomas Steckler, Alyson J Bond, Alex Hofer, Stefan Leucht, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Irwin Lucki, Fadi T. Maalouf, David A. Brent, David A. Brent, Fadi Maalouf, Alex Hofer, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Huaiyu Yang, George I. Papakostas, Andrew Young, Gabriele Fischer, Annemarie Unger, Linda P Spear, Linda P Spear, Mohammed Shoaib, Emma Childs, Britta Hahn, Peter Boeijinga, Martine Cador, David S Tait, Verity J. Brown, Martine Cador, David Baldwin, Yavin Shaham, Sunila G Nair, Yavin Shaham, Sunila G Nair, Matthew I Palmatier, Rick A Bevins, Peter Riederer, Siegfried Hoyer, Mark Geyer, Anthony Absalom, David Menon, Joseph Zohar, Stephen C Fowler, James Winslow, Kim Wolff, Bankole A. Johnson, Martina de Zwaan, Alyson J Bond, Angela Roberts, Anthony R Isles, Lawrence S. Wilkinson, Anthony R Isles, Lawrence S. Wilkinson, Rosa M M de Almeida, Klaus A. Miczek, Eric Nestler, Naheed (Max) Mirza, Bankole A Johnson, Joseph H Friedman, István Bitter, Michael Minzenberg, Lawrence H. Price, Ashwini Padhi, Naomi Fineberg, Michael M Morgan, MacDonald J. Christie, Lawrence H. Price, Joris C. Verster, Bernard Le Foll, Marilyn E Carroll, Peter A Santi, Ronald F Mucha, Ian P. Stolerman, Richard W Foltin, Michael Minzenberg, Christoph Hiemke, Luis Stinus, Stéphanie Caillé, Martine Cador, Yavin Shaham, John R Mantsch, Ronald F Mucha, Kim Wolff, Anthony L. Riley, Steve Kohut, Brian E. Leonard, Joseph Zohar, R. Andrew Chambers, Gail Winger, Mei-Chuan Ko, James H Woods, Huaiyu Yang, George I. Papakostas, Michael M Morgan, MacDonald J. Christie, Seiya Miyamoto, Thomas R. E. Barnes, Kieran O’Malley, Luis Stinus, Stéphanie Caillé, Martine Cador, David J. Hellerstein, Thomas R. E. Barnes   +141 more
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Dissociative Anesthetics

2015
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Ketamine a dissociative anesthetic: Neurobiology and biomolecular exploration in depression

Chemico-Biological Interactions, 2020
Ketamine is gaining ground as a potential treating depression because it has a distinct mode of action than typical drugs that influence monoamine neurotransmitters including noradrenaline, dopamine, or serotonin. Ketamine is thought to act by blocking N-methyl-d-aspartate (NMDA) receptors in the brain, which interact with the amino acid ...
Guo-Liang, Liu, Yun-Feng, Cui, Chang, Lu, Peng, Zhao   +3 more
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Patinet Acceptance of Dissociative Anesthetics

Plastic and Reconstructive Surgery, 1983
A prospective study was undertaken to evaluate the efficacy, safety, and patient acceptance of low-dose ketamine when used to diminish the pain of local anesthetic injections. The role of diazepam in preventing the untoward psychological effects of ketamine was also investigated.
B L, Cunningham, P, McKinney
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Dissociative Anesthetics in the Cat and Dog

Journal of the American Veterinary Medical Association, 1972
SUMMARY Dissociative anesthetic agents have the potential to revolutionize the anesthetic management of the dog and cat. They may become an integral part of a regimen of “balanced anesthesia” in veterinary medicine. The dissociative state produced by these agents is characterized by muscle rigidity and the presence of many reflexes (e.g., swallowing ...
D W, DeYoung, R R, Paddleford, C E, Short   +2 more
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Ketamine induces EEG oscillations that may aid anesthetic state but not dissociation monitoring

Clinical Neurophysiology, 2021
Ketamine is an anesthetic drug associated with dissociation. Decreased electroencephalogram alpha (8-13 Hz) and low-beta (13-20 Hz) oscillation power have been associated with ketamine-induced dissociation. We aimed to characterize surface electroencephalogram signatures that may serve as biomarkers for dissociation.We analyzed data from a single-site,
Shubham Chamadia, Jacob Gitlin, Jennifer Mekonnen, Breanna R. Ethridge, Reine Ibala, Katia M. Colon, Jason Qu, Oluwaseun Akeju   +7 more
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A simplified 6-Item clinician administered dissociative symptom scale (CADSS-6) for monitoring dissociative effects of sub-anesthetic ketamine infusions

Journal of Affective Disorders, 2021
Dissociation is a treatment-emergent adverse event commonly associated with IV ketamine, often measured using the 23-item Clinician-Administered Dissociative States Scale (CADSS). The objective of this study was to develop a short form version of the CADSS for easier clinical use.Retrospective data of 260 patients with treatment-resistant depression ...
Nelson B. Rodrigues, Roger S. McIntyre, Orly Lipsitz, Yena Lee, Danielle S. Cha, Margarita Shekotikhina, Maj Vinberg, Hartej Gill, Mehala Subramaniapillai, Kevin Kratiuk, Kangguang Lin, Roger Ho, Rodrigo B. Mansur, Joshua D. Rosenblat   +13 more
openaire   +3 more sources