Results 51 to 60 of about 46,948 (289)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Dissociation and pain perception : an experimental investigation [PDF]
, 2006 textDissociative symptoms and abnormalities in pain perception have been associated with a range of disorders. We tested whether experimentally induced increases in state dissociation would cause an analgesic response, and whether this effect would be ...
Horowitz, Jonathan David
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Elektra complex in dissociative identity disorder: A case report
European Psychiatry, 2021 Introduction Dissociative identity disorder is a quite popular psychiatric diagnosis in general public but in actuality has a very low prevalence rate.
P. Jain, V. Mudgal, U. Sardesai, V. Pal
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Can dissociative amnesia be a residual symptom of prolonged complex post-traumatic stress disorder?
Annals of General PsychiatryBackground Dissociative amnesia, a disorder characterized by impairments in multiple memory areas, is frequently associated with trauma. Complex post-traumatic stress disorder (CPTSD) is marked by mood dysregulation, negative self-concept, and impaired ...
İzzet Çağrı Metin +2 more
doaj +1 more source
Mirror Writing and a Dissociative Identity Disorder
Case Reports in Medicine, 2009 Individuals with dissociative identity disorder (DID) have been known to show varied skills and talents as they change from one dissociative state to another.
Catherine Le, Joyce Smith, Lewis Cohen
doaj +1 more source
A Non-linear Predictive Model of Borderline Personality Disorder Based on Multilayer Perceptron
Frontiers in Psychology, 2018 Borderline Personality Disorder is a serious mental disease, classified in Cluster B of DSM IV-TR personality disorders. People with this syndrome presents an anamnesis of traumatic experiences and shows dissociative symptoms.
Nelson M. Maldonato +3 more
doaj +1 more source
European Journal of Psychotraumatology, 2022 Background: Post-traumatic stress disorder (PTSD) with dissociative symptoms is now a full-fledged subtype of this disorder. The dissociative subtype is associated with a greater number of psychiatric comorbidities. To date, the impact of dissociation on
Pascal Roullet +6 more
doaj +1 more source