Results 51 to 60 of about 1,098,265 (205)

A Non-linear Predictive Model of Borderline Personality Disorder Based on Multilayer Perceptron

Frontiers in Psychology, 2018
Borderline Personality Disorder is a serious mental disease, classified in Cluster B of DSM IV-TR personality disorders. People with this syndrome presents an anamnesis of traumatic experiences and shows dissociative symptoms.
Nelson M. Maldonato, Raffaele Sperandeo, Enrico Moretto, Silvia Dell'Orco   +3 more
doaj   +1 more source

Efficacy of traumatic memory reactivation with or without propranolol in PTSD with high dissociative experiences

European Journal of Psychotraumatology, 2022
Background: Post-traumatic stress disorder (PTSD) with dissociative symptoms is now a full-fledged subtype of this disorder. The dissociative subtype is associated with a greater number of psychiatric comorbidities. To date, the impact of dissociation on
Pascal Roullet, Simon Taïb, Claire Thalamas, Guillaume Vaiva, Wissam El Hage, Antoine Yrondi, Philippe Birmes   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Differentiating multiple personality disorder and dissociative disorder not otherwise specified [PDF]

, 1992
p. 087-090The authors interviewed 166 patients with clinical diagnoses of multiple personality disorder and 57 with diagnoses of dissociative disorder not otherwise specified with the Dissociative Experiences Scale and the Dissociative Disorders ...
Ross, Colin A., Fraser, George A., Miller, Scott D., Bjornson, Lynda, Reagor, Pamela A., Anderson, Geri   +5 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A survey of dissociation, boundary-thinness, and psychological wellbeing in spiritualist mental mediumship [PDF]

, 2011
The purpose of this study was to explore the personality and psychological wellbeing of Spiritualist mental mediums compared to nonmedium Spiritualists.
Roxburgh, EC, Roe, CA, Roe, Chris A, Roe, Chris A; id_orcid, Roxburgh, Elizabeth C   +4 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Dissociazione e alessitimia in un campione di pazienti con Disturbo del Comportamento Alimentare

Research in Psychotherapy, 2010
The aim of this study has been to investigate the dissociative phenomena and the difficulties related to perceive, understand and describe the proper ones and other people's emotional states in a sample of 53 patients with Eating Disorders. The recruited
Marco La Marra, Walter Sapuppo, Giorgio Caviglia   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Complex dissociation following maternal suicide attempt in a 17-year-old female: a case report

Journal of Medical Case Reports
Background Dissociative disorders involve disruptions in memory, identity, sensory awareness, and motor control, often triggered by psychological distress.
Shota Hanyu
doaj   +1 more source