Results 41 to 50 of about 1,295,201 (280)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Somatoform and Dissociative Disorders [PDF]
, 2005 Key Points\ud \ud • The somatoform disorders are psychiatric illnesses that present as physical disorders. \ud • The somatoform disorders are not to be confused with malingering which is the intentional production of symptoms to avoid some responsibility
Elder, Ruth L.
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
BMC Psychiatry, 2021 Background Dissociative (conversion) disorder in children is a complex biopsychosocial disorder with high rates of medical and psychiatric comorbidities.
Zhixu Fang +7 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Interacciones, 2023 Introduction: The Dissociative Experiences Scale (DES-II) is a widely used psychometric tool to assess dissociative symptoms. Over the years, it has been the subject of numerous studies and research in various fields of psychology and psychiatry ...
Juan González-Rivera
doaj +1 more source
Dissociative identity disorder and partial dissociative identity disorder
Deutsches Ärzteblatt internationalThe diagnosis dissociative identity disorder (DID) replaces multiple personality disorder in the ICD-11. It is characterized by the presence of two or more distinct personality states (dissociative identities) and, typically, by amnesia from one state to another.
Stefan, Roepke +5 more
openaire +2 more sources
Dissociative disorders among alcohol-dependent inpatients
, 2021 The aim of this study was to determine the prevalence of dissociative disorders among inpatients with alcohol dependency. The Dissociative Experiences Scale was used to screen I I I alcohol-dependent patients consecutively admitted to the inpatient unit ...
Evren, Curteyt +4 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Relationships between Dissociative Disorders and Personality Traits in Opium Addicts on Methadone Treatment [PDF]
Addiction and Health, 2013 Background: Drug abuse is a major public health problem. Some believe that when dissociation fails to defend against emotional, physical, or sexual trauma, the person will find relief from unpleasant thoughts and emotions in opium use. On the other hand,
Alireza Ghafarinezhad +2 more
doaj