Results 51 to 60 of about 15,417 (244)

Pojęcie „dysocjacji” – zagadnienia podstawowe

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2014
In this article I present the notion the dissociation. The dissociation is connected with personality disorders and with the trauma. Experience a strong trauma is nature of dissociative disorders.
Wioletta Jedlecka
doaj   +1 more source

PTSD presenting as possession states in children and adolescents in rural Sri Lanka: a case series

open access: yesSri Lanka Journal of Psychiatry, 2020
Dissociative disorders are usually a result of trauma and stress. They may stem from chronic trauma such as repeated episodes of physical, emotional, or sexual abuse or may follow acute trauma.
J. Herath, S. R. Perera
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Dissociative Symptoms in Anxiety Disorders [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2014
Dissosiyasyon, belirli kosullar altinda herkeste ortaya cikabilecek uyumsal bir mekanizmadir. Baslangicta travmatik yasantilarin ustesinden gelme amaciyla kullanilirken zamanla patolojik bir surece donustugu ve bir bozukluk olarak nitelendirildigi ...
Merve Tekin, Atilla Tekin
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A review of the dissociative disorders: from multiple personality disorder to the posttraumatic stress

open access: yesAnales de Psicologia
In this paper we review the idea of dissociation, dissociative disorders and their relationship with the processes of consciousness. We will deal specifically with multiple personality disorder and posttraumatic stress disorder.
Modesto J. Romero-López
doaj   +1 more source

Child Trauma Experiences and Dissociative Symptoms in Women with Eating Disorders: Case-Control Study

open access: yesChildren, 2020
Background: many people with different diagnoses, including eating disorders, have suffered traumatic experiences in childhood. Method: a case-control study was performed.
María F. Rabito-Alcón   +2 more
doaj   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

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