Results 71 to 80 of about 18,024 (282)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Somatoform and dissociative disorders

, 2009
• The somatoform disorders are psychiatric illnesses that present as physical disorders.\ud • The somatoform disorders are not to be confused with malingering, which is the intentional production of symptoms to avoid some responsibility or duty.\ud ...
Elder, Ruth
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

A review of the dissociative disorders: from multiple personality disorder to the posttraumatic stress

Anales de Psicologia
In this paper we review the idea of dissociation, dissociative disorders and their relationship with the processes of consciousness. We will deal specifically with multiple personality disorder and posttraumatic stress disorder.
Modesto J. Romero-López
doaj   +1 more source

Suicide Risk in Dissociative Disorders.

, 2007
Since the 1980s, after a period of neglect in the mid-20th Century, there has been a reawakening of interest in dissociative disorders. The aim of this paper is to describe the epidemiology and diagnostic classification of dissociative disorders and ...
LESTER D, Marco, Innamorati, DEL CASALE, ANTONIO, GALEANDRO PM, TATARELLI, Roberto, POMPILI, Maurizio, David, Lester, INNAMORATI M   +7 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Prevalence of dissociative identity disorder among psychiatric outpatients in different cultural groups

Middle East Current Psychiatry
Background Dissociative disorders (DDs) are characterized by a disturbance in the organization of identity, consciousness, perception, or memory. This disturbance involves disruptions of consciousness and limited access to information.
May Mahmoud Abdellah, Khadiga Mohamed Ragheb, Taghreed Mohamed Elshafie, Rania Ahmed Hamed   +3 more
doaj   +1 more source

Somatoform and Dissociative Disorders

, 2005
Key Points\ud \ud • The somatoform disorders are psychiatric illnesses that present as physical disorders. \ud • The somatoform disorders are not to be confused with malingering which is the intentional production of symptoms to avoid some responsibility
Elder, Ruth L.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source