Results 41 to 50 of about 909,392 (302)

Development, Validation and Approbation Analytical Method for the Quantitative Determination of Taurine by HPLC-UV Method in the Test of Comparative Dissolution Kinetics

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. Taurine is a non-proteinogenic amino acid. The molecule is involved in lipid metabolism, adsorbs fat-soluble vitamins, and its conjugates with bile acids contribute to the emulsification of fats in the intestine.
A. M. Poluyanov   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The kinetics of the dissolution of chalcopyrite in chloride media [PDF]

open access: yes, 2009
One of the most important outstanding problems with the hydrometallurgy of copper is the low temperature leaching of chalcopyrite. In this thesis, a fundamental study at low temperature was undertaken in order to establish a mechanism, which is ...
Velásquez Yévenes, Lilian
core  

Microstructure Evolution in Homogenization Heat Treatment of Inconel 718 Manufactured by Laser Powder Bed Fusion

open access: yesMetals
This study systematically investigates the homogenization-induced Laves phase dissolution kinetics and recrystallization mechanisms in laser powder bed fusion (L-PBF) processed IN718 superalloy.
Fang Zhang, Yifu Shen, Haiou Yang
doaj   +1 more source

The interplay of dissolution, solution crystallization and solid-state transformation of amorphous indomethacin in aqueous solution

open access: yesInternational Journal of Pharmaceutics: X, 2020
Supersaturation profiles of amorphous indomethacin in aqueous solution containing 0.4 wt% and 4 wt% of isopropanol were predicted by combining separately-determined kinetics for dissolution, solution crystallization, and solid-state transformation.
Raj Schneider   +6 more
doaj   +1 more source

Cavitation-assisted decontamination of yttria from graphite of different densities

open access: yesUltrasonics Sonochemistry, 2021
Yttria coated graphite crucibles are widely used to handle molten refractory and radioactive metals like uranium and plutonium. However, the coated layer suffers damages like cracking and peeling off owing to thermal cycles.
S. Lahiri   +4 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The dissolution of gold colloids in aqueous thiosulfate solutions [PDF]

open access: yes, 2008
The kinetics of the dissolution of gold and silver colloids in ammoniacal thiosulfate solutions has been studied using oxygen, copper(II) or oxygenated copper(II) as oxidants at pH 9 - 11 and temperature 22oC to 48oC.
Zhang, Xinmin
core  

Drug transport mechanisms from carbopol/eudragit verapamil sustained-release tablets [PDF]

open access: yes, 2011
The objectives of this study were to compare dissolution profiles of a verapamil (VRP) formulation manufactured inhouse and Isoptin SR using USP Apparatus 2 and 3 and to elucidate drug release kinetics of these dosage forms.
Roderick B. Walker   +3 more
core   +2 more sources

The effects of ultrasonic cavitation on the dissolution of lithium disilicate glass

open access: yesScientific Reports, 2022
There has been little research conducted on how ultrasonic cavitation may affect glass dissolution. The focus of this study was to examine how the mechanisms and kinetics of glass dissolution may change in a system that included ultrasonication ...
Ben Dillinger   +2 more
doaj   +1 more source

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